The Swedish Renal Registry: a nationwide registry for chronic kidney disease of all stages.

IF 4.6 2区医学 Q1 UROLOGY & NEPHROLOGY

Clinical Kidney Journal Pub Date : 2025-08-06 eCollection Date: 2025-09-01 DOI:10.1093/ckj/sfaf238

Anne-Laure Faucon, Helena Rydell, Maria Stendahl, Gunilla Welander, Torbjörn Lundgren, Karl-Göran Prûtz, Staffan Schön, Ursa Bonnevier, Aline Kåveryd Hult, Håkan Hedman, Frida Fondelius, Mårten Segelmark, Marie Evans

{"title":"The Swedish Renal Registry: a nationwide registry for chronic kidney disease of all stages.","authors":"Anne-Laure Faucon, Helena Rydell, Maria Stendahl, Gunilla Welander, Torbjörn Lundgren, Karl-Göran Prûtz, Staffan Schön, Ursa Bonnevier, Aline Kåveryd Hult, Håkan Hedman, Frida Fondelius, Mårten Segelmark, Marie Evans","doi":"10.1093/ckj/sfaf238","DOIUrl":null,"url":null,"abstract":"Background: National registries that capture patients with chronic kidney disease (CKD) across all stages are scarce. We present here the Swedish Renal Registry (SRR), a nationwide prospective register covering the whole spectrum of CKD.Methods: Created in 1991, SRR enrolls CKD patients referred to adult nephrologist care (non-dialysis CKD [ND-CKD], kidney transplantation, maintenance dialysis), with an overall coverage of nearly all nephrology clinics in Sweden. SRR encompasses several interconnected databases in which longitudinal clinical, biological, kidney-related, patient-reported data, as well as provider-level information are collected. This report presents the design of the registry, as well as patients characteristics and temporal trends between 2008 and 2021.Results: A total of 45 590 new ND-CKD patients [72 years, 16 656 (36%) women, eGFR 26 ml/min per 1.73 m²], and 8829 incident kidney transplant recipients (51 years, 35% women) were enrolled in SRR between 2008 and 2021. SRR also included 16 034 new patients [68 years, 5420 (34%) women] on maintenance dialysis [70% hemodialysis (HD), 30% peritoneal dialysis (PD)]. Between 2015 and 2021, 4753 patients [59 years, 1884 (40%) women, eGFR 37 ml/min per 1.73 m²] had a registered kidney biopsy. We observed a decrease in HD incidence (69% to 60%, P for trend <.01) and an increase in PD incidence (26% to 32%, P < .01) and pre-emptive transplantation (4.7% to 7.5%, P < .01). The prevalence of comorbidities is high in all CKD stages and increase as eGFR declines. While nephroangiosclerosis and diabetic kidney disease are the most common etiologies, glomerulonephritis are the most frequent diagnoses in biopsied and transplanted patients.Conclusion: The SRR is a nationwide register which aims to contribute to address gaps in our understanding of CKD, to identify important challenges and health priorities, evaluate real-life clinical management and analyze international variations, improve health outcomes, improve quality of life, and reduce the burden of CKD.","PeriodicalId":10435,"journal":{"name":"Clinical Kidney Journal","volume":"18 9","pages":"sfaf238"},"PeriodicalIF":4.6000,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421726/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Kidney Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/ckj/sfaf238","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: National registries that capture patients with chronic kidney disease (CKD) across all stages are scarce. We present here the Swedish Renal Registry (SRR), a nationwide prospective register covering the whole spectrum of CKD.

Methods: Created in 1991, SRR enrolls CKD patients referred to adult nephrologist care (non-dialysis CKD [ND-CKD], kidney transplantation, maintenance dialysis), with an overall coverage of nearly all nephrology clinics in Sweden. SRR encompasses several interconnected databases in which longitudinal clinical, biological, kidney-related, patient-reported data, as well as provider-level information are collected. This report presents the design of the registry, as well as patients characteristics and temporal trends between 2008 and 2021.

Results: A total of 45 590 new ND-CKD patients [72 years, 16 656 (36%) women, eGFR 26 ml/min per 1.73 m²], and 8829 incident kidney transplant recipients (51 years, 35% women) were enrolled in SRR between 2008 and 2021. SRR also included 16 034 new patients [68 years, 5420 (34%) women] on maintenance dialysis [70% hemodialysis (HD), 30% peritoneal dialysis (PD)]. Between 2015 and 2021, 4753 patients [59 years, 1884 (40%) women, eGFR 37 ml/min per 1.73 m²] had a registered kidney biopsy. We observed a decrease in HD incidence (69% to 60%, P for trend <.01) and an increase in PD incidence (26% to 32%, P < .01) and pre-emptive transplantation (4.7% to 7.5%, P < .01). The prevalence of comorbidities is high in all CKD stages and increase as eGFR declines. While nephroangiosclerosis and diabetic kidney disease are the most common etiologies, glomerulonephritis are the most frequent diagnoses in biopsied and transplanted patients.

Conclusion: The SRR is a nationwide register which aims to contribute to address gaps in our understanding of CKD, to identify important challenges and health priorities, evaluate real-life clinical management and analyze international variations, improve health outcomes, improve quality of life, and reduce the burden of CKD.

Abstract Image

查看原文本刊更多论文

瑞典肾脏登记：所有阶段慢性肾脏疾病的全国性登记。

背景：覆盖所有阶段慢性肾脏疾病（CKD）患者的国家登记是稀缺的。我们在此介绍瑞典肾脏登记处（SRR），一个覆盖整个CKD范围的全国性前瞻性登记处。方法：创建于1991年，SRR纳入了成人肾脏科护理的CKD患者（非透析CKD [ND-CKD]，肾移植，维持透析），几乎覆盖了瑞典所有肾脏科诊所。SRR包括几个相互关联的数据库，其中收集了纵向临床，生物学，肾脏相关，患者报告的数据以及提供者级别的信息。本报告介绍了登记处的设计，以及2008年至2021年期间的患者特征和时间趋势。结果：在2008年至2021年期间，共有45590名新发ND-CKD患者（72岁，16656（36%）名女性，eGFR为26 ml/min / 1.73 m²）和8829名肾移植受者（51岁，35%女性）被纳入SRR。SRR还纳入了16 034例新的维持性透析患者[68岁，5420例（34%）女性][70%血液透析（HD）， 30%腹膜透析（PD）]。2015年至2021年间，4753例患者（59岁，1884例（40%）女性，eGFR 37 ml/min / 1.73 m²）进行了登记的肾活检。结论：SRR是一个全国性的登记册，旨在解决我们对CKD的理解差距，确定重要的挑战和健康优先事项，评估现实生活中的临床管理并分析国际差异，改善健康结果，提高生活质量，减轻CKD的负担。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical Kidney Journal Medicine-Transplantation

CiteScore

6.70

自引率

10.90%

发文量

242

审稿时长

8 weeks

期刊介绍： About the Journal Clinical Kidney Journal: Clinical and Translational Nephrology (ckj), an official journal of the ERA-EDTA (European Renal Association-European Dialysis and Transplant Association), is a fully open access, online only journal publishing bimonthly. The journal is an essential educational and training resource integrating clinical, translational and educational research into clinical practice. ckj aims to contribute to a translational research culture among nephrologists and kidney pathologists that helps close the gap between basic researchers and practicing clinicians and promote sorely needed innovation in the Nephrology field. All research articles in this journal have undergone peer review.