{"title":"Should allergic sensitization be assessed in patients with eosinophilic gastrointestinal diseases under dietary treatment before reintroduction?","authors":"Gizem Koken, Hacer Ilbilge Ertoy Karagol, Sinem Polat Terece, Demet Teker Duztas, Odul Egritas Gurkan, Sinan Sari, Buket Dalgic, Arzu Bakirtas","doi":"10.5415/apallergy.0000000000000204","DOIUrl":null,"url":null,"abstract":"<p><p>Primary eosinophilic gastrointestinal diseases (EGIDs) are defined by recurring or persistent gastrointestinal symptoms with histopathological eosinophilic inflammation, after excluding secondary causes. Food elimination diets (FEDs) are one of the main treatment options for primary EGIDs. Sensitization and immunoglobulin E (IgE)-mediated hypersensitivity reactions to eliminated foods after dietary restriction were reported in only a small number of patients with EGIDs. Here, a pediatric EGID patient was described who experienced anaphylaxis after the reintroduction of cow's milk post-FED. In addition, cases of primary EGID patients developing IgE-mediated hypersensitivity reactions to once-tolerated foods after elimination diets were reviewed.</p>","PeriodicalId":8488,"journal":{"name":"Asia Pacific Allergy","volume":"15 3","pages":"232-234"},"PeriodicalIF":2.1000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419354/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asia Pacific Allergy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5415/apallergy.0000000000000204","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/31 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ALLERGY","Score":null,"Total":0}
引用次数: 0
Abstract
Primary eosinophilic gastrointestinal diseases (EGIDs) are defined by recurring or persistent gastrointestinal symptoms with histopathological eosinophilic inflammation, after excluding secondary causes. Food elimination diets (FEDs) are one of the main treatment options for primary EGIDs. Sensitization and immunoglobulin E (IgE)-mediated hypersensitivity reactions to eliminated foods after dietary restriction were reported in only a small number of patients with EGIDs. Here, a pediatric EGID patient was described who experienced anaphylaxis after the reintroduction of cow's milk post-FED. In addition, cases of primary EGID patients developing IgE-mediated hypersensitivity reactions to once-tolerated foods after elimination diets were reviewed.
期刊介绍：
Asia Pacific Allergy (AP Allergy) is the official journal of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI). Although the primary aim of the journal is to promote communication between Asia Pacific scientists who are interested in allergy, asthma, and clinical immunology including immunodeficiency, the journal is intended to be available worldwide. To enable scientists and clinicians from emerging societies appreciate the scope and intent of the journal, early issues will contain more educational review material. For better communication and understanding, it will include rational concepts related to the diagnosis and management of asthma and other immunological conditions. Over time, the journal will increase the number of original research papers to become the foremost citation journal for allergy and clinical immunology information of the Asia Pacific in the future.
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