{"title":"Stochastic Diffusivity With Time-Varying Trajectory in Mobile Molecular Communication: Performance Analysis and Channel Modeling","authors":"Nihit Bhatnagar;Sandeep Joshi","doi":"10.1109/TMBMC.2025.3558109","DOIUrl":null,"url":null,"abstract":"This work considers a three-dimensional mobile molecular communication (MC) with intra-body disease spread applications. The communicating devices in the considered mobile MC system are point transmitters and passive spherical receiver nano-machines (NMs) with emitted information-carrying molecules following the Gaussian Brownian motion. These NMs can be used to detect the presence of disease spread and for targeted drug delivery. We propose stochastic diffusivity models for both communicating devices and information-carrying molecules. Using the stochastic diffusivity model and considering initial distance as a reference, we derive the probability density function of the relative distance between the communicating devices. We allocate the time-varying trajectory to the information-carrying molecules moving towards receiver NM and obtain its diffusivity distribution. Through the proposed stochastic diffusivity model, we characterize the mobile MC channel by channel impulse response and derive its statistical mean. We consider the discrete-time statistical channel model at a high inter-symbol interference regime and analyze the channel performance in terms of error analysis and receiver operating characteristics. We also derive the channel capacity for the considered system model. We show the degree of accuracy through root mean square error for the Poisson and Gaussian distribution models. Furthermore, the numerical results are verified through particle-based simulations.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"11 3","pages":"359-370"},"PeriodicalIF":2.3000,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","FirstCategoryId":"1085","ListUrlMain":"https://ieeexplore.ieee.org/document/10949637/","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
引用次数: 0
Abstract
This work considers a three-dimensional mobile molecular communication (MC) with intra-body disease spread applications. The communicating devices in the considered mobile MC system are point transmitters and passive spherical receiver nano-machines (NMs) with emitted information-carrying molecules following the Gaussian Brownian motion. These NMs can be used to detect the presence of disease spread and for targeted drug delivery. We propose stochastic diffusivity models for both communicating devices and information-carrying molecules. Using the stochastic diffusivity model and considering initial distance as a reference, we derive the probability density function of the relative distance between the communicating devices. We allocate the time-varying trajectory to the information-carrying molecules moving towards receiver NM and obtain its diffusivity distribution. Through the proposed stochastic diffusivity model, we characterize the mobile MC channel by channel impulse response and derive its statistical mean. We consider the discrete-time statistical channel model at a high inter-symbol interference regime and analyze the channel performance in terms of error analysis and receiver operating characteristics. We also derive the channel capacity for the considered system model. We show the degree of accuracy through root mean square error for the Poisson and Gaussian distribution models. Furthermore, the numerical results are verified through particle-based simulations.
期刊介绍:
As a result of recent advances in MEMS/NEMS and systems biology, as well as the emergence of synthetic bacteria and lab/process-on-a-chip techniques, it is now possible to design chemical “circuits”, custom organisms, micro/nanoscale swarms of devices, and a host of other new systems. This success opens up a new frontier for interdisciplinary communications techniques using chemistry, biology, and other principles that have not been considered in the communications literature. The IEEE Transactions on Molecular, Biological, and Multi-Scale Communications (T-MBMSC) is devoted to the principles, design, and analysis of communication systems that use physics beyond classical electromagnetism. This includes molecular, quantum, and other physical, chemical and biological techniques; as well as new communication techniques at small scales or across multiple scales (e.g., nano to micro to macro; note that strictly nanoscale systems, 1-100 nm, are outside the scope of this journal). Original research articles on one or more of the following topics are within scope: mathematical modeling, information/communication and network theoretic analysis, standardization and industrial applications, and analytical or experimental studies on communication processes or networks in biology. Contributions on related topics may also be considered for publication. Contributions from researchers outside the IEEE’s typical audience are encouraged.