Encapsulated Hydrogels Enhance Sulfamethoxazole Removal via Structure-Driven Microbial Metabolisms

IF 6.7 Q1 ENGINEERING, ENVIRONMENTAL

ACS ES&T engineering Pub Date : 2025-06-19 DOI:10.1021/acsestengg.5c00342

Xinrui Lin, Zhipeng Xu, Feng Lin, Peizu Ruan, Ting Li, Shiying Chen, Qidong Yin*, Kai He* and Shanquan Wang,

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Abstract

The widespread occurrence of antibiotics in aquatic environments poses serious ecological and public health risks, necessitating advanced treatment strategies. Biohydrogels present a versatile platform for enhancing the removal of sulfamethoxazole (SMX) by combining adsorption with microbial degradation. In this study, polyvinyl alcohol-sodium alginate (PVA-SA) hydrogels were used to immobilize anaerobic sludge, forming two hydrogel systems (gel7.5 and gel9) with distinct physical structures. Both systems achieved significantly higher SMX removal efficiencies (90.2 and 87.7%) compared with the control (67.7%). Metagenomic analysis revealed differential enrichment of key SMX-degrading genera, with Lentimicrobium dominant in gel7.5 and Pseudomonas and Acinetobacter enriched in gel9. Functional gene profiling further indicated that gel7.5 and gel9 favored distinct monooxygenase pathways for SMX transformation. These results demonstrate that the hydrogel composition shapes microbial community function and biodegradation mechanisms, offering an effective and adaptable solution for treating antibiotic-contaminated wastewater while mitigating the risk of resistance gene dissemination.

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胶囊化水凝胶通过结构驱动的微生物代谢增强磺胺甲恶唑的去除

抗生素在水生环境中的广泛存在造成了严重的生态和公共卫生风险，需要先进的治疗策略。生物水凝胶通过吸附和微生物降解相结合，为提高磺胺甲恶唑（SMX）的去除提供了一个通用的平台。本研究采用聚乙烯醇-海藻酸钠（PVA-SA）水凝胶固定化厌氧污泥，形成两种物理结构不同的凝胶体系gel7.5和gel9。两种体系的SMX去除率（分别为90.2%和87.7%）均显著高于对照（67.7%）。宏基因组分析显示smx关键降解属的富集差异，其中lentimicroum在gel7.5中占优势，假单胞菌和不动杆菌在gel9中富集。功能基因分析进一步表明gel7.5和gel9倾向于SMX转化的不同单加氧酶途径。这些结果表明，水凝胶组成决定了微生物群落功能和生物降解机制，为处理抗生素污染废水提供了一种有效且适应性强的解决方案，同时降低了耐药性基因传播的风险。

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来源期刊

ACS ES&T engineering ENGINEERING, ENVIRONMENTAL-

CiteScore

8.50

自引率

0.00%

发文量

期刊介绍： ACS ES&T Engineering publishes impactful research and review articles across all realms of environmental technology and engineering, employing a rigorous peer-review process. As a specialized journal, it aims to provide an international platform for research and innovation, inviting contributions on materials technologies, processes, data analytics, and engineering systems that can effectively manage, protect, and remediate air, water, and soil quality, as well as treat wastes and recover resources. The journal encourages research that supports informed decision-making within complex engineered systems and is grounded in mechanistic science and analytics, describing intricate environmental engineering systems. It considers papers presenting novel advancements, spanning from laboratory discovery to field-based application. However, case or demonstration studies lacking significant scientific advancements and technological innovations are not within its scope. Contributions containing experimental and/or theoretical methods, rooted in engineering principles and integrated with knowledge from other disciplines, are welcomed.