Tracing Erich Sackmann's Journey from Liquid Crystals to Biological Membranes.

IF 3.1 3区生物学 Q2 BIOPHYSICS

Biophysical journal Pub Date : 2025-09-11 DOI:10.1016/j.bpj.2025.09.014

Laurent Vonna,Laurent Limozin,Jacques Prost,Kheya Sengupta

引用次数: 0

Abstract

Biological membranes and liquid crystals are closely related because they exhibit similar types of molecular ordering and symmetry. This deep connection led many researchers in the '60s and '70s to cross back and forth between the two domains of research. Erich Sackmann crossed over early in his career, taking concepts and techniques from liquid crystal physics to membrane biology, and stayed to provide unique insights into the organisation and behaviour of membranes, helping to lay the foundations of physics of biological membranes and biophysics as we know it today. His mastery of liquid crystalline order, phase transition, anisotropy, and dynamics, naturally led him to fundamental properties of membrane-stacks, membranes and cytoskeletal mechanics. He helped establish simplified "model membranes" as a powerful tool to isolate and study specific aspects of membrane behaviour under controlled conditions and transfer this knowledge to biology.

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追溯Erich Sackmann从液晶到生物膜的历程。

生物膜和液晶密切相关，因为它们表现出相似的分子有序和对称性。这种深刻的联系导致60年代和70年代的许多研究人员在这两个研究领域之间来回穿梭。埃里希·萨克曼在他的职业生涯早期跨越，从液晶物理到膜生物学的概念和技术，并留下对膜的组织和行为提供独特的见解，帮助奠定了我们今天所知道的生物膜和生物物理学的物理学基础。他对液晶顺序、相变、各向异性和动力学的掌握，自然使他了解了膜堆、膜和细胞骨架力学的基本特性。他帮助建立了简化的“模型膜”，作为一种强大的工具，在受控条件下分离和研究膜行为的特定方面，并将这些知识转移到生物学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biophysical journal 生物-生物物理

CiteScore

6.10

自引率

5.90%

发文量

3090

审稿时长

2 months

期刊介绍： BJ publishes original articles, letters, and perspectives on important problems in modern biophysics. The papers should be written so as to be of interest to a broad community of biophysicists. BJ welcomes experimental studies that employ quantitative physical approaches for the study of biological systems, including or spanning scales from molecule to whole organism. Experimental studies of a purely descriptive or phenomenological nature, with no theoretical or mechanistic underpinning, are not appropriate for publication in BJ. Theoretical studies should offer new insights into the understanding ofexperimental results or suggest new experimentally testable hypotheses. Articles reporting significant methodological or technological advances, which have potential to open new areas of biophysical investigation, are also suitable for publication in BJ. Papers describing improvements in accuracy or speed of existing methods or extra detail within methods described previously are not suitable for BJ.