[ניתוחים להטיית מערכת השתן עם או ללא כריתת שלפוחית השתן בהוריה של מחלה לא ממאירה: ניסיון רב שנים של מרכז שלישוני].

Harefuah Pub Date : 2025-09-01
Amir Buchler, Hadar Tamir, Chen Shenhar, Roi Babaoff, Daniel Kedar, Gabriel Gilon, Jack Baniel, Shachar Aharony
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Abstract

Introduction: Urinary diversion, with or without cystectomy, is a radical option for individuals experiencing end-stage lower urinary tract dysfunction caused by non-malignant bladder conditions. Our aim was to highlight our experience with this procedure, focusing particularly on its safety.

Methods: Demographic, clinical, and surgical data were collected for patients who underwent the procedure. Postoperative complications were examined and classified into short-term (<30 days) and long-term (>30 days) complications.

Results: Twenty-three patients (48% women, median age 60 years (IQR:44-67 years)) underwent urinary diversion for benign indications. Eight (35%) and six (26%) patients, underwent urinary diversion without cystectomy and supra-trigonal cystectomy respectively. The most common indications for surgery were a non-functioning bladder due to, oncological treatments (39%), neurogenic bladder (17%) and refractory interstitial cystitis (13%). Postoperative complications were recorded in 60% of patients, with 87% of these being low-grade complications (Clavien-Dindo ≤2). Two patients experienced late complications, and one patient died three months after surgery due to septic shock. No complications or need for additional cystectomy were documented in patients who underwent urinary diversion alone.

Conclusions: Urinary diversion, with or without cystectomy, is an effective and relatively safe solution for refractory end-stage bladder dysfunction. The surgery improves the quality of life and coping for patients with a non-functioning bladder. Despite the potential surgical complications, it should be considered as a last resort when other conservative treatments have failed. Further studies with larger cohorts are needed to validate these findings.

导读:对于非恶性膀胱疾病引起的终末期下尿路功能障碍患者,尿改道(伴或不伴膀胱切除术)是一种激进的选择。我们的目的是强调我们在这一过程中的经验,特别关注其安全性。方法:收集接受手术的患者的人口学、临床和手术资料。检查术后并发症并将其分为短期(30天)并发症。结果:23例患者(48%为女性,中位年龄60岁(IQR:44-67岁))因良性适应症行尿路转移。8例(35%)和6例(26%)患者分别行尿分流而不行膀胱切除术和三角上膀胱切除术。最常见的手术指征是肿瘤治疗导致的膀胱功能障碍(39%)、神经源性膀胱(17%)和难治性间质性膀胱炎(13%)。60%的患者出现术后并发症,其中87%为低级别并发症(Clavien-Dindo≤2)。2例患者出现晚期并发症,1例患者术后3个月因感染性休克死亡。单独行尿分流的患者无并发症或需要额外的膀胱切除术。结论:输尿管改道,不论有无膀胱切除术,都是治疗难治性终末期膀胱功能障碍的有效且相对安全的方法。手术改善了膀胱功能障碍患者的生活质量和应对能力。尽管有潜在的手术并发症,但当其他保守治疗失败时,它应被视为最后的手段。需要更大规模的进一步研究来验证这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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