{"title":"Efficacy of cellular and/or tissue-based product applications on all non-pressure injury chronic wound types in a Medicare private practice model.","authors":"Shaun Carpenter, Angelina Ferguson, Devinna Bahadur, Amanda Estapa, Jamie Bahm, Sadie Burst","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This retrospective analysis is a derivative cohort study based on a prior retrospective investigation by this author group.</p><p><strong>Objective: </strong>To assess the effect of the number of cellular and/or tissue-based product (CTP) applications on healing outcomes and wound area reduction (WAR) rates in patients with chronic wounds of multiple etiologies.</p><p><strong>Methods: </strong>Data from a multicenter private wound care practice electronic health record database were analyzed for Medicare patients receiving CTPs from January 2018 through December 2023. Wound treatments were administered in nursing homes (4.77%), private clinics (80.11%), and home settings (15.65%), excluding hospital outpatient department settings. This retrospective analysis evaluated WAR and closure rates following each CTP application.</p><p><strong>Results: </strong>A total of 446 wounds were included in the analysis, comprising 123 diabetic foot ulcers (DFUs), 134 venous leg ulcers (VLUs), 62 surgical wounds, 51 trauma wounds, and 76 other chronic wounds. Significant reductions in average wound areas (cm²) were observed after completing the CTP application series (ie, ≤10 CTPs within 16 weeks) for all chronic wounds (P < .001). Further, there were more total healed wounds noted for the chronic surgical and trauma wounds compared with DFUs and VLUs.</p><p><strong>Conclusion: </strong>This retrospective real-world analysis of Medicare patients undergoing CTP therapy in conjunction with standard of care for chronic trauma and surgical wounds demonstrates substantial reductions in wound area following completion of a CTP application series. Findings from this study may guide governing bodies regarding CTP best practice recommendations in the treatment of chronic wounds of various etiologies.</p>","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":"37 8","pages":"292-304"},"PeriodicalIF":1.1000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wounds : a compendium of clinical research and practice","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: This retrospective analysis is a derivative cohort study based on a prior retrospective investigation by this author group.
Objective: To assess the effect of the number of cellular and/or tissue-based product (CTP) applications on healing outcomes and wound area reduction (WAR) rates in patients with chronic wounds of multiple etiologies.
Methods: Data from a multicenter private wound care practice electronic health record database were analyzed for Medicare patients receiving CTPs from January 2018 through December 2023. Wound treatments were administered in nursing homes (4.77%), private clinics (80.11%), and home settings (15.65%), excluding hospital outpatient department settings. This retrospective analysis evaluated WAR and closure rates following each CTP application.
Results: A total of 446 wounds were included in the analysis, comprising 123 diabetic foot ulcers (DFUs), 134 venous leg ulcers (VLUs), 62 surgical wounds, 51 trauma wounds, and 76 other chronic wounds. Significant reductions in average wound areas (cm²) were observed after completing the CTP application series (ie, ≤10 CTPs within 16 weeks) for all chronic wounds (P < .001). Further, there were more total healed wounds noted for the chronic surgical and trauma wounds compared with DFUs and VLUs.
Conclusion: This retrospective real-world analysis of Medicare patients undergoing CTP therapy in conjunction with standard of care for chronic trauma and surgical wounds demonstrates substantial reductions in wound area following completion of a CTP application series. Findings from this study may guide governing bodies regarding CTP best practice recommendations in the treatment of chronic wounds of various etiologies.
期刊介绍：
Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies.
Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more.
Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.
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