Semantic processing in subjective cognitive decline: An eye-tracking study.

IF 3 3区心理学 Q3 NEUROSCIENCES

Neuropsychology Pub Date : 2025-10-01 Epub Date: 2025-09-11 DOI:10.1037/neu0001022

Marc-Antoine Akzam-Ouellette, Isabelle Rouleau, Laura Monetta, Maxime Descoteaux, Sven Joubert

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引用次数: 0

Abstract

Objectives: Alzheimer's disease progresses through several stages, starting with a preclinical phase characterized by subjective cognitive decline (SCD), where individuals express concerns about their memory despite normal cognitive test results. Recent research has indicated subtle semantic difficulties in SCD, prompting the need for a deeper investigation into cognitive processing during this phase. This study aimed to investigate the cognitive processing of famous and unfamiliar faces in individuals with SCD compared to healthy controls, focusing on semantic memory deficits assessment.

Method: Twenty-seven participants with SCD and 26 control participants performed a judgment task involving famous and unfamiliar faces while their eye movements were recorded. Mean fixation times, number of revisitations, and number of fixations were analyzed between the two groups.

Results: The SCD group exhibited no significant differences in mean fixation times and in the number of revisited regions between famous and unfamiliar faces, in contrast to the control group, which showed distinct patterns in processing these categories of stimuli.

Conclusion: These findings suggest that individuals with SCD process famous faces similarly to unfamiliar faces, indicating a potential weakening of semantic processing in SCD. This may have implications for early detection of cognitive decline in Alzheimer's disease. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

查看原文本刊更多论文

主观认知衰退中的语义加工：一项眼动追踪研究。

目的：阿尔茨海默病的进展经历几个阶段，从以主观认知衰退（SCD）为特征的临床前阶段开始，尽管认知测试结果正常，但个体仍表达对其记忆的担忧。最近的研究表明，SCD中存在微妙的语义困难，这促使人们需要对这一阶段的认知加工进行更深入的研究。本研究旨在探讨SCD患者与健康对照者对著名面孔和不熟悉面孔的认知加工，重点关注语义记忆缺陷的评估。方法：记录27名SCD患者和26名对照组的眼球运动，并对熟悉面孔和不熟悉面孔进行判断。分析两组患者的平均注视时间、重访次数和注视次数。结果：与对照组相比，SCD组在注视著名面孔和陌生面孔的平均注视时间和重访区域数量上没有显著差异，但在处理这些类型的刺激时，SCD组表现出不同的模式。结论：SCD个体对知名面孔的加工与不熟悉面孔相似，提示SCD语义加工可能减弱。这可能对阿尔茨海默病认知能力下降的早期检测有影响。（PsycInfo Database Record (c) 2025 APA，版权所有）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuropsychology 医学-神经科学

CiteScore

4.10

自引率

4.20%

发文量

132

审稿时长

6-12 weeks

期刊介绍： Neuropsychology publishes original, empirical research; systematic reviews and meta-analyses; and theoretical articles on the relation between brain and human cognitive, emotional, and behavioral function.