{"title":"Relational accountability in AI-driven pharmaceutical practices: an ethics approach to bias, inequity and structural harm.","authors":"Irfan Biswas","doi":"10.1136/jme-2025-110913","DOIUrl":null,"url":null,"abstract":"<p><p>The integration of artificial intelligence (AI) into pharmaceutical practices raises critical ethical concerns, including algorithmic bias, data commodification and global health inequities. While existing AI ethics frameworks emphasise transparency and fairness, they often overlook structural vulnerabilities tied to race, gender and socioeconomic status. This paper introduces relational accountability-a feminist ethics framework-to critique AI-driven pharmaceutical practices, arguing that corporate reliance on biased algorithms exacerbates inequalities by design. Through case studies of Pfizer-IBM Watson's immuno-oncology collaboration and Google DeepMind's National Health Service partnership, we demonstrate how AI entrenches disparities in drug pricing, access and development. We propose a causal pathway linking biased training data to inequitable health outcomes, supported by empirical evidence of AI-driven price discrimination and exclusionary clinical trial recruitment algorithms. Policy solutions, including algorithmic audits and equity-centred data governance, are advanced to realign AI with the ethical imperative. This work bridges feminist bioethics and AI governance, offering a novel lens to address structural harm in healthcare innovation.</p>","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Ethics","FirstCategoryId":"98","ListUrlMain":"https://doi.org/10.1136/jme-2025-110913","RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ETHICS","Score":null,"Total":0}
引用次数: 0
Abstract
The integration of artificial intelligence (AI) into pharmaceutical practices raises critical ethical concerns, including algorithmic bias, data commodification and global health inequities. While existing AI ethics frameworks emphasise transparency and fairness, they often overlook structural vulnerabilities tied to race, gender and socioeconomic status. This paper introduces relational accountability-a feminist ethics framework-to critique AI-driven pharmaceutical practices, arguing that corporate reliance on biased algorithms exacerbates inequalities by design. Through case studies of Pfizer-IBM Watson's immuno-oncology collaboration and Google DeepMind's National Health Service partnership, we demonstrate how AI entrenches disparities in drug pricing, access and development. We propose a causal pathway linking biased training data to inequitable health outcomes, supported by empirical evidence of AI-driven price discrimination and exclusionary clinical trial recruitment algorithms. Policy solutions, including algorithmic audits and equity-centred data governance, are advanced to realign AI with the ethical imperative. This work bridges feminist bioethics and AI governance, offering a novel lens to address structural harm in healthcare innovation.
期刊介绍:
Journal of Medical Ethics is a leading international journal that reflects the whole field of medical ethics. The journal seeks to promote ethical reflection and conduct in scientific research and medical practice. It features articles on various ethical aspects of health care relevant to health care professionals, members of clinical ethics committees, medical ethics professionals, researchers and bioscientists, policy makers and patients.
Subscribers to the Journal of Medical Ethics also receive Medical Humanities journal at no extra cost.
JME is the official journal of the Institute of Medical Ethics.