String-of-pearls: Extensive medium vessel vasculitis associated with childhood lupus.

IF 1.9 4区 医学 Q3 RHEUMATOLOGY
Lupus Pub Date : 2025-10-01 Epub Date: 2025-09-10 DOI:10.1177/09612033251378387
Saurabh Agarwal, Aliza Mittal, Lokesh Saini, Paras Tewari, Sarbesh Tiwari, Taruna Yadav, Siyaram Didel
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引用次数: 0

Abstract

Case details: A 16-year boy had a history of rash, oral ulcers, alopecia, photosensitivity, cheilitis, and weight loss, for which he was started on steroids, methotrexate, and hydroxychloroquine from outside. Three years later, he developed pericardial effusion and peripheral neuropathy, that were managed at an outside hospital. Later, he presented to us with weight loss, diffuse rash, left facial palsy, and left lateral rectus palsy. CT aortogram revealed a string-of-pearls appearance involving the head, neck, thoracic, and visceral arteries. The child was diagnosed with severe lupus vasculitis with minimal systemic symptoms. This child responded well to the methylprednisolone and cyclophosphamide.Conclusions: This is a unique example of the classical multisystemic presentation of lupus and its rare manifestation of extensive systemic vasculitis.

珍珠串:与儿童狼疮相关的广泛的中等血管炎。
病例细节:一名16岁男孩,有皮疹、口腔溃疡、脱发、光敏性、唇炎和体重减轻的病史,为此他从外部开始使用类固醇、甲氨蝶呤和羟氯喹。三年后,他出现心包积液和周围神经病变,在一家外部医院进行了治疗。后来,他出现体重减轻、弥漫性皮疹、左侧面瘫和左侧外侧直肌麻痹。CT主动脉造影显示一串珍珠状外观,累及头、颈、胸及内脏动脉。该儿童被诊断为严重狼疮血管炎,全身症状轻微。这名儿童对甲基强的松龙和环磷酰胺反应良好。结论:这是一个典型的狼疮多系统表现的独特例子,其罕见的表现是广泛的系统性血管炎。
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来源期刊
Lupus
Lupus 医学-风湿病学
CiteScore
4.20
自引率
11.50%
发文量
225
审稿时长
1 months
期刊介绍: The only fully peer reviewed international journal devoted exclusively to lupus (and related disease) research. Lupus includes the most promising new clinical and laboratory-based studies from leading specialists in all lupus-related disciplines. Invaluable reading, with extended coverage, lupus-related disciplines include: Rheumatology, Dermatology, Immunology, Obstetrics, Psychiatry and Cardiovascular Research…
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