{"title":"Host transfer RNA guides assembly of viral RNA polymerase","authors":"","doi":"10.1038/s41594-025-01654-x","DOIUrl":null,"url":null,"abstract":"Transfer RNAs (tRNAs) are best known for their role in decoding messenger RNA codons and translating them into amino acids. A comprehensive biochemical and structural investigation of the poxviral transcription apparatus uncovers a thus far unknown role of specific host tRNAs as assembly chaperones for a multisubunit RNA polymerase complex.","PeriodicalId":18822,"journal":{"name":"Nature structural & molecular biology","volume":"18 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature structural & molecular biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s41594-025-01654-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Transfer RNAs (tRNAs) are best known for their role in decoding messenger RNA codons and translating them into amino acids. A comprehensive biochemical and structural investigation of the poxviral transcription apparatus uncovers a thus far unknown role of specific host tRNAs as assembly chaperones for a multisubunit RNA polymerase complex.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
