Nature structural & molecular biology

Computational design of sequence-specific DNA-binding proteins

Pub Date : 2025-09-12 DOI: 10.1038/s41594-025-01669-4 Cameron J. Glasscock, Robert J. Pecoraro, Ryan McHugh, Lindsey A. Doyle, Wei Chen, Olivier Boivin, Beau Lonnquist, Emily Na, Yuliya Politanska, Hugh K. Haddox, David Cox, Christoffer Norn, Brian Coventry, Inna Goreshnik, Dionne Vafeados, Gyu Rie Lee, Raluca Gordân, Barry L. Stoddard, Frank DiMaio, David Baker

Host transfer RNA guides assembly of viral RNA polymerase

Pub Date : 2025-09-10 DOI: 10.1038/s41594-025-01654-x

A snapshot of proteostasis in human oocytes

Pub Date : 2025-09-09 DOI: 10.1038/s41594-025-01679-2 Dimitris Typas