An Approach to Drug Discovery via Ethnopharmacology and Sustainable Agriculture.

Abstract

Ethnopharmacology is the study of traditional medicinal knowledge and its application in modern drug discovery. It combines ethnobotanical insights with scientific research to identify bio-active compounds with therapeutic potential. Sustainable agriculture refers to farming practices that maintain ecological balance, support biodiversity, and ensure the long-term availability of resources. Integrating these fields can enhance drug discovery while preserving medicinal plants and promoting environmental sustainability. This review examines the collaboration between ethnopharmacology and sustainable agriculture in advancing drug discovery, conservation, and global food security. This review examines the role of ethnopharmacology in drug discovery, analyzing traditional medicinal practices, bioactivity-guided fractionation, and metabolomic profiling. It also investigates sustainable agriculture techniques, including organic farming, controlled cultivation, and conservation strategies for medicinal plants. Data were collected from peer-reviewed literature using sources such as Google Scholar, PubMed, Scopus, and journal databases like ScienceDirect. Ethnopharmacology has con-tributed to the discovery of key drugs with anticancer, anti-inflammatory, and antimicrobial proper-ties. Sustainable agriculture ensures a steady supply of medicinal plants while optimizing their bio-active compound production through improved cultivation techniques. The combination of these ap-proaches strengthens drug discovery efforts and supports ecological conservation. Integrating eth-nopharmacology with sustainable agriculture is a promising strategy for developing new drugs while protecting natural resources. Future research should focus on innovative cultivation techniques, com-munity-led conservation efforts, and advanced analytical methods to enhance the discovery of new drugs. The adoption of agroecological practices, technological advancements, and policy support will be crucial in ensuring sustainable and equitable benefits for healthcare and agriculture. Bridging tra-ditional knowledge with scientific research will foster new therapeutic discoveries while promoting environmental sustainability.