Synergistic effects of Bacillus subtilis QST 713 and L-arginine supplementation during late gestation on reproductive performance in Landrace × Yorkshire sows: A randomized controlled trial.
Thepsavanh Khoudphaithoune, Do Thi Kim Lanh, Nguyen Van Thanh, Bui Van Dung, Peerapol Sukon, Nguyen Hoai Nam
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引用次数: 0
Abstract
Background and aim: Low birth weight and within-litter variations are major challenges in swine production, often exacerbated by highly prolific sow lines. Nutritional interventions such as amino acid and probiotic supplementation have shown promise, but their combined effects remain unexplored. This study aimed to evaluate the individual and interactive effects of Bacillus subtilis QST 713 and L-arginine supplementation during late gestation on reproductive performance in sows.
Materials and methods: A randomized trial was conducted on 247 Landrace × Yorkshire sows allocated to four dietary groups from day 85 of gestation to farrowing: (1) Basal diet (control), (2) basal diet + B. subtilis, (3) basal diet + L-arginine, and (4) basal diet + both supplements. Reproductive outcomes-including individual birth weight (IBW), total litter birth weight (TBW), born-alive birth weight (NBABW), proportion of runt (<1.1 kg) and large piglets (>1.5 kg), and within-litter coefficient of variation in birth weight [CVBW])-were assessed. Linear and generalized linear mixed models were used for analysis.
Results: Co-supplementation with B. subtilis and L-arginine significantly increased IBW (1434.7 g vs. 1310.0 g, p < 0.001), TBW (19.6 kg vs. 16.9 kg, p < 0.001), NBABW (18.1 kg vs. 15.9 kg, p = 0.006), and the proportion of large piglets (33.7% vs. 19.5%, p = 0.0002), while reducing runt piglet incidence (4.0% vs. 14.4%, p < 0.001). Neither supplement alone produced significant improvements. No treatment significantly affected litter size, CVBW, stillbirth, or mummification rates.
Conclusion: Co-supplementation of sows with B. subtilis and L-arginine during late gestation produces synergistic impro-vements in piglet birth weight and litter quality. This strategy offers a practical and cost-effective approach to enhance swine reproductive efficiency.
背景和目的：低出生体重和窝内变异是猪生产中的主要挑战，高产母猪往往会加剧这种挑战。补充氨基酸和益生菌等营养干预措施已显示出前景，但它们的综合效果仍未得到探索。本研究旨在评价妊娠后期添加枯草芽孢杆菌QST 713和l -精氨酸对母猪繁殖性能的单独影响和交互作用。材料与方法：选用247头长×大母猪，从妊娠第85天开始至分娩，随机分为4个饲粮组：(1)基础饲粮（对照）、(2)基础饲粮+枯草芽孢杆菌、(3)基础饲粮+ l -精氨酸、(4)基础饲粮+两种添加物。评估繁殖结果，包括个体出生体重（IBW）、窝产总体重（TBW）、活产出生体重（NBABW）、幼崽比例（1.5 kg）和窝内出生体重变异系数（CVBW）。采用线性和广义线性混合模型进行分析。结果：枯草芽孢杆菌与l -精氨酸共添加显著提高了仔猪IBW （1434.7 g vs. 1310.0 g, p < 0.001）、TBW （19.6 kg vs. 16.9 kg, p < 0.001）、NBABW （18.1 kg vs. 15.9 kg, p = 0.006）和大头仔猪比例（33.7% vs. 19.5%, p = 0.0002），降低了小头仔猪发生率（4.0% vs. 14.4%, p < 0.001）。两种补充剂都不能单独产生显著的改善。没有治疗显著影响产仔数、CVBW、死胎或木乃伊化率。结论：妊娠后期母猪共添加枯草芽孢杆菌和l -精氨酸可协同提高仔猪初生重和产仔质量。该策略为提高猪的繁殖效率提供了一种实用且经济的方法。
期刊介绍：
Veterinary World publishes high quality papers focusing on Veterinary and Animal Science. The fields of study are bacteriology, parasitology, pathology, virology, immunology, mycology, public health, biotechnology, meat science, fish diseases, nutrition, gynecology, genetics, wildlife, laboratory animals, animal models of human infections, prion diseases and epidemiology. Studies on zoonotic and emerging infections are highly appreciated. Review articles are highly appreciated. All articles published by Veterinary World are made freely and permanently accessible online. All articles to Veterinary World are posted online immediately as they are ready for publication.
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