Effectiveness of high-frequency repetitive transcranial magnetic stimulation coupled with rehabilitation in patients with spinal cord injury: a systematic review.

IF 1.5 4区医学 Q3 CLINICAL NEUROLOGY

Neurological Research Pub Date : 2025-09-09 DOI:10.1080/01616412.2025.2558860

Rudraksh Banga, Kavin Devani, Kanwal Preet Kochhar, Suman Jain

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引用次数: 0

Abstract

Background: Spinal Cord Injury (SCI) leads to partial or complete sensorimotor loss because of the spinal lesions caused either by trauma or any pathological conditions. Rehabilitation, one of the therapeutic methods, is considered to be a significant part of therapy supporting patients with spinal cord injury. Newer methods are being incorporated, such as repetitive Transcranial Magnetic Stimulation (rTMS), a Non-Invasive Brain Stimulation (NIBS) technique to induce changes in the residual neuronal pathways, facilitating cortical excitability and neuroplasticity.

Study design: PRISMA-guided systematic review.

Objective: To comprehend the therapeutic efficacy of rTMS combined with rehabilitation in SCI patients by evaluating the results reported in previous studies.

Methodology: An online electronic search was executed on the scientific databases, PUBMED, COCHRANE LIBRARY, and SCOPUS using the keywords: 'Spinal Cord Injury (SCI),' 'repetitive Transcranial Magnetic Stimulation (rTMS),' and 'rehabilitation' and articles published in the English language between the years 2010 to 2024 were screened and extracted based on the eligibility criteria according to PICOS framework.

Results: Four full-text articles were selected and analysed. Following HF-rTMS and neuro-rehabilitation, significant upper and lower extremity functional gains marked by UEMS & LEMS and a reduction in lower limb spasticity were reported by MAS scores in active SCI groups.

Conclusion: To modulate corticospinal tract fiber excitability and reduce spasticity in patients with SCI, HF-rTMS shows promising therapeutic effects if combined with a rehabilitation program.

Prospero id: CRD420251028333.

查看原文本刊更多论文

高频重复经颅磁刺激结合康复治疗脊髓损伤患者的有效性：系统综述。

背景：脊髓损伤（SCI）可导致部分或完全的感觉运动丧失，这是由于脊髓损伤或任何病理条件引起的。康复是治疗方法之一，是支持脊髓损伤患者治疗的重要组成部分。新的方法正在被纳入，如重复经颅磁刺激（rTMS），一种非侵入性脑刺激（NIBS）技术，以诱导残留神经元通路的变化，促进皮层兴奋性和神经可塑性。研究设计：prisma引导的系统评价。目的：通过对已有研究结果的评价，了解rTMS联合康复治疗脊髓损伤的疗效。方法：在科学数据库PUBMED、COCHRANE LIBRARY和SCOPUS中进行在线电子检索，检索关键词为“脊髓损伤（SCI）”、“重复经颅磁刺激（rTMS）”和“康复”，并根据PICOS框架的资格标准筛选和提取2010年至2024年间发表的英文文章。结果：选取4篇全文文章进行分析。在进行HF-rTMS和神经康复治疗后，活动性脊髓损伤组的MAS评分显示，UEMS和LEMS标志着显著的上肢和下肢功能增加，下肢痉挛减少。结论：HF-rTMS与康复治疗相结合，可调节脊髓损伤患者的皮质脊髓束纤维兴奋性，减少痉挛。普洛斯彼罗id: CRD420251028333。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurological Research 医学-临床神经学

CiteScore

3.60

自引率

0.00%

发文量

116

审稿时长

5.3 months

期刊介绍： Neurological Research is an international, peer-reviewed journal for reporting both basic and clinical research in the fields of neurosurgery, neurology, neuroengineering and neurosciences. It provides a medium for those who recognize the wider implications of their work and who wish to be informed of the relevant experience of others in related and more distant fields. The scope of the journal includes: •Stem cell applications •Molecular neuroscience •Neuropharmacology •Neuroradiology •Neurochemistry •Biomathematical models •Endovascular neurosurgery •Innovation in neurosurgery.