Quality of Life, Disability, and Fungal Neglected Tropical Diseases.

IF 3.3 Q3 INFECTIOUS DISEASES

Current Fungal Infection Reports Pub Date : 2025-04-01 DOI:10.1007/s12281-025-00503-0

Alyson M Cavanaugh, Amanda Ribeiro Dos Santos, Dayvison Francis Saraiva Freitas, James Venturini, Ahmed Fahal, Conceição Azevedo, Jeremy A W Gold

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引用次数: 0

Abstract

Purpose of review: This review summarizes current literature about the disability burden of the fungal neglected tropical diseases (NTDs) sporotrichosis, chromoblastomycosis, eumycetoma, and paracoccidioidomycosis. The review highlights current knowledge gaps in global settings and describes available tools that could be adopted to fill these gaps.

Recent findings: Sporotrichosis, chromoblastomycosis, and eumycetoma often present initially as skin lesions that can become progressively disfiguring, lead to stigmatization, and cause various sequalae affecting health and function. Chronic paracoccidioidomycosis can have systemic involvement and commonly results in impaired pulmonary function, which can limit activities of daily living and employment capacity. Use of standardized tools to quantify disability with fungal NTDs has been limited to date. Standardized tools to measure the impacts on quality of life and mental health are available and have been used for similar patient populations, including persons with other fungal diseases and persons with non-fungal skin NTDs.

Summary: Fungal NTDs can be disabling. Improved understanding of the quality of life and mental health consequences might lead to greater awareness of the burden of fungal NTDs and enhance health planning to address the health and rehabilitation needs of persons affected by these diseases.

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生活质量、残疾和被真菌忽视的热带病。

综述目的：本文综述了目前关于真菌被忽视的热带病（NTDs）孢子菌病、成色菌病、真菌肿和副球孢子菌病的致残负担的文献。该审查强调了目前全球背景下的知识差距，并描述了可用于填补这些差距的可用工具。最近发现：孢子菌病、成色菌病和尘菌瘤最初通常表现为皮肤病变，可逐渐毁容，导致污名化，并引起各种影响健康和功能的后遗症。慢性副球孢子菌病可累及全身，通常导致肺功能受损，从而限制日常生活活动和就业能力。迄今为止，使用标准化工具来量化真菌性被忽视热带病的致残性受到限制。现有衡量对生活质量和精神健康影响的标准化工具，并已用于类似的患者群体，包括患有其他真菌疾病的人和患有非真菌皮肤被忽视热带病的人。总结：真菌结核分枝杆菌可致残。提高对生活质量和精神健康后果的了解，可能会提高对真菌性被忽视热带病负担的认识，并加强卫生规划，以满足受这些疾病影响者的健康和康复需求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Fungal Infection Reports INFECTIOUS DISEASES-

CiteScore

3.10

自引率

7.10%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of fungal infections. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as advances in diagnosis, current and emerging management approaches, and genomics and pathogenesis. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. Commentaries from well-known figures in the field are also provided, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.