Multimodal Psychobehavioral Interventions for Lung Cancer-Related Pain: A Protocol Development and Validation Study Examining the Mediating Role of Self-Efficacy in the Relationship Between Pain Perception and Adaptive Coping Strategies.

IF 2.6 4区医学 Q3 ONCOLOGY

Cancer Management and Research Pub Date : 2025-09-02 eCollection Date: 2025-01-01 DOI:10.2147/CMAR.S537477

Bing Liu, Yongyong Ding, Junfei Xu, Xuehai Wu, Xiaofeng Yang, Yi Liu, Hong Deng

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Abstract

Objective: To evaluate the effects of a comprehensive intervention program on cancer pain and self-efficacy in patients with lung cancer.

Methods: A total of 120 lung cancer patients with cancer pain who received treatment from January 2021 to December 2023 at The First People's Hospital of Zunyi were enrolled in this study. A within-subject design was used, comparing patients' pain and self-efficacy scores before and after a comprehensive intervention. The intervention included pharmacologic therapy, psychological counseling, health education, mindfulness training, social support, and personalized rehabilitation. Pain was assessed using the Numerical Rating Scale (NRS), and self-efficacy was measured with the Chronic Disease Self-Efficacy Scale (CDSE). Subgroup and regression analyses were performed to explore related factors.

Results: After intervention, the average NRS pain score decreased significantly from 7.2 ± 1.5 to 3.8 ± 1.2 (↓47.22%, t=15.6, p<0.001). Patients participating in mindfulness training reported a greater reduction in pain than non-participants (p=0.013). The total CDSE score increased from 52.3 ± 8.7 to 72.4 ± 9.5 (t=12.4, p<0.001), with significant improvements across all subscales (self-management, general efficacy, goal achievement, and problem-solving; all p<0.001). Subgroup analyses revealed that the improvements were consistent across gender, age groups, and education levels (p>0.05). Logistic regression identified pain relief (NRS score) as a significant predictor of enhanced self-efficacy (OR=1.403, 95% CI: 1.125-1.885, p=0.002), whereas age and education were not significant.

Conclusion: A comprehensive, multimodal intervention significantly improved both pain control and self-efficacy in patients with lung cancer-related pain. The effects were robust across demographic subgroups, with pain relief being a key factor influencing self-efficacy. These findings support the integration of psychological and behavioral strategies in pain management for cancer patients.

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肺癌相关疼痛的多模式心理行为干预：自我效能感在疼痛感知与适应性应对策略关系中的中介作用的方案制定与验证研究

目的：评价综合干预方案对肺癌患者癌症疼痛和自我效能感的影响。方法：选取2021年1月至2023年12月在遵义市第一人民医院接受治疗的肺癌癌性疼痛患者120例为研究对象。采用受试者内设计，比较综合干预前后患者的疼痛和自我效能评分。干预措施包括药物治疗、心理咨询、健康教育、正念训练、社会支持和个性化康复。采用数值评定量表（NRS）评定疼痛，采用慢性疾病自我效能量表（CDSE）评定自我效能。进行亚组分析和回归分析，探讨相关因素。结果：干预后NRS疼痛平均评分由7.2 ± 1.5降至3.8 ± 1.2（↓47.22%,t=15.6, p0.05）。Logistic回归发现疼痛缓解（NRS评分）是自我效能增强的重要预测因子（OR=1.403, 95% CI: 1.125-1.885, p=0.002），而年龄和教育程度无显著影响。结论：综合、多模式干预可显著改善肺癌相关疼痛患者的疼痛控制和自我效能感。在人口统计亚组中，疼痛缓解是影响自我效能的关键因素。这些发现支持心理和行为策略在癌症患者疼痛管理中的整合。

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来源期刊

Cancer Management and Research Medicine-Oncology

CiteScore

7.40

自引率

0.00%

发文量

448

审稿时长

16 weeks

期刊介绍： Cancer Management and Research is an international, peer reviewed, open access journal focusing on cancer research and the optimal use of preventative and integrated treatment interventions to achieve improved outcomes, enhanced survival, and quality of life for cancer patients. Specific topics covered in the journal include: ◦Epidemiology, detection and screening ◦Cellular research and biomarkers ◦Identification of biotargets and agents with novel mechanisms of action ◦Optimal clinical use of existing anticancer agents, including combination therapies ◦Radiation and surgery ◦Palliative care ◦Patient adherence, quality of life, satisfaction The journal welcomes submitted papers covering original research, basic science, clinical & epidemiological studies, reviews & evaluations, guidelines, expert opinion and commentary, and case series that shed novel insights on a disease or disease subtype.