Ivermectin toxicosis in a foal: Use of intravenous lipid emulsion therapy.

IF 1 4区农林科学 Q3 VETERINARY SCIENCES

Canadian Veterinary Journal-revue Veterinaire Canadienne Pub Date : 2025-09-01

Shannon Darby, SallyAnne DeNotta, Diego E Gomez

引用次数: 0

Abstract

This report describes a case of ivermectin toxicosis in a 4-day-old thoroughbred colt successfully treated with intravenous lipid emulsion (ILE) without complications. This case supports the use of ILE as a safe and effective therapy for the management of lipophilic drug toxicosis in foals. Key clinical message: Ivermectin toxicosis, though rare in equine neonates, can occur following accidental overdose and induces severe neurologic signs. In this case, ILE administration resulted in rapid neurologic improvement and complete recovery without adverse effects, supporting its use as a safe and effective antidote for lipophilic drug toxicosis in foals.

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马驹伊维菌素中毒：静脉脂质乳剂治疗的应用。

本报告描述了一例伊维菌素中毒的4日龄纯种马成功治疗静脉脂质乳剂（ILE）无并发症。本病例支持使用ILE作为一种安全有效的治疗马驹亲脂性药物中毒的方法。关键临床信息：伊维菌素中毒，虽然罕见的马新生儿，可发生意外过量，并诱发严重的神经系统症状。在这种情况下，ILE给药导致了快速的神经系统改善和完全恢复，没有不良反应，支持其作为一种安全有效的解毒剂用于马驹的亲脂性药物中毒。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Canadian Veterinary Journal-revue Veterinaire Canadienne 农林科学-兽医学

CiteScore

1.20

自引率

10.00%

发文量

177

审稿时长

12-24 weeks

期刊介绍： The Canadian Veterinary Journal (CVJ) provides a forum for the discussion of all matters relevant to the veterinary profession. The mission of the Journal is to educate by informing readers of progress in clinical veterinary medicine, clinical veterinary research, and related fields of endeavor. The key objective of The CVJ is to promote the art and science of veterinary medicine and the betterment of animal health. A report suggesting that animals have been unnecessarily subjected to adverse, stressful, or harsh conditions or treatments will not be processed for publication. Experimental studies using animals will only be considered for publication if the studies have been approved by an institutional animal care committee, or equivalent, and the guidelines of the Canadian Council on Animal Care, or equivalent, have been followed by the author(s).