K. Venkatesan, Hussain Shaik, Md Kadeer, V. Suryanarayana, P. Karthikeyan
{"title":"Mini Review on Total Synthesis of Antihypertensive Drug Telmisartan","authors":"K. Venkatesan, Hussain Shaik, Md Kadeer, V. Suryanarayana, P. Karthikeyan","doi":"10.1134/S1070363225603072","DOIUrl":null,"url":null,"abstract":"<p>A chronic illness that is prevalent throughout the globe, hypertension is a major probability factor for cardiovascular disease. An angiotensin receptor blocker may be a better initial antihypertensive medication for patients who are resistant to angiotensin-converting enzyme inhibiting agents, such as telmisartan. Telmisartan can be used either alone or in conjunction with other medications that lower blood pressure. This review covers the various synthetic methodologies used for the preparation of telmisartan and their characterization for structural elucidation.</p>","PeriodicalId":761,"journal":{"name":"Russian Journal of General Chemistry","volume":"95 8","pages":"1924 - 1935"},"PeriodicalIF":0.8000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of General Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070363225603072","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A chronic illness that is prevalent throughout the globe, hypertension is a major probability factor for cardiovascular disease. An angiotensin receptor blocker may be a better initial antihypertensive medication for patients who are resistant to angiotensin-converting enzyme inhibiting agents, such as telmisartan. Telmisartan can be used either alone or in conjunction with other medications that lower blood pressure. This review covers the various synthetic methodologies used for the preparation of telmisartan and their characterization for structural elucidation.
期刊介绍:
Russian Journal of General Chemistry is a journal that covers many problems that are of general interest to the whole community of chemists. The journal is the successor to Russia’s first chemical journal, Zhurnal Russkogo Khimicheskogo Obshchestva (Journal of the Russian Chemical Society ) founded in 1869 to cover all aspects of chemistry. Now the journal is focused on the interdisciplinary areas of chemistry (organometallics, organometalloids, organoinorganic complexes, mechanochemistry, nanochemistry, etc.), new achievements and long-term results in the field. The journal publishes reviews, current scientific papers, letters to the editor, and discussion papers.