Hydrogen-bond-mediated supramolecular polyhedra

IF 7.4 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Science China Materials Pub Date : 2025-08-20 DOI:10.1007/s40843-025-3568-4

Ran-Qi Chen (, ), Feiyue Liu (, ), Yujie Xing (, ), Jiayi Wang (, ), Aspen X.-Y. Chen (, ), Yu Wang (, ), Huang Wu (, )

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Abstract

Many viral capsids with spherical structures represent the most exemplary polyhedral architectures in nature, with icosahedral symmetry being particularly prototypical. These polyhedral capsids are formed through the spontaneous self-assembly of multiple identical protein subunits via non-covalent interactions following precisely symmetry-matching rules. Inspired by this biological self-assembly mechanism, the construction of biomimetic polyhedra has emerged as a prominent research focus in supramolecular chemistry. Notwithstanding the significant challenges in structural stability and geometric precision control faced by hydrogen bond-directed polyhedral assembly systems, these supramolecular constructs exhibit extraordinary promise in synthetic chemistry and materials science, owing to their distinctive dynamic responsiveness, reversible assembly behavior, and versatile structural designability. This review methodically categorizes the structural types of hydrogen-bonded supramolecular polyhedra and their building block characteristics, explores key scientific challenges in the field, and further outlines future research trends. The work hopes to establish a theoretical framework and methodological guidance for the controlled assembly and functionalization of bioinspired hydrogen-bonded polyhedral structures, thereby advancing supramolecular materials toward precision and intelligent development.

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氢键介导的超分子多面体

许多具有球形结构的病毒衣壳代表了自然界中最典型的多面体结构，其中二十面体对称尤为典型。这些多面体衣壳是通过遵循精确对称匹配规则的非共价相互作用，通过多个相同的蛋白质亚基自发自组装而形成的。受这种生物自组装机制的启发，仿生多面体的构建已成为超分子化学领域的一个重要研究热点。尽管氢键导向多面体组装系统在结构稳定性和几何精度控制方面面临重大挑战，但这些超分子结构由于其独特的动态响应性、可逆的组装行为和多用途的结构可设计性，在合成化学和材料科学中表现出非凡的前景。本文对氢键超分子多面体的结构类型及其组成单元特征进行了系统的分类，探讨了该领域的关键科学挑战，并进一步概述了未来的研究趋势。本工作希望为仿生氢键多面体结构的受控组装和功能化建立理论框架和方法指导，从而推动超分子材料向精密化和智能化方向发展。

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来源期刊

Science China Materials Materials Science-General Materials Science

CiteScore

11.40

自引率

7.40%

发文量

949

期刊介绍： Science China Materials (SCM) is a globally peer-reviewed journal that covers all facets of materials science. It is supervised by the Chinese Academy of Sciences and co-sponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China. The journal is jointly published monthly in both printed and electronic forms by Science China Press and Springer. The aim of SCM is to encourage communication of high-quality, innovative research results at the cutting-edge interface of materials science with chemistry, physics, biology, and engineering. It focuses on breakthroughs from around the world and aims to become a world-leading academic journal for materials science.