Continuity of HIV and hepatitis C care in times of war – Five Times Ninety project

IF 4 3区医学 Q1 INFECTIOUS DISEASES

Journal of Infection and Public Health Pub Date : 2025-09-01 DOI:10.1016/j.jiph.2025.102950

Justyna D. Kowalska , Bartłomiej Matłosz , Olena Samsonova , Sergii Antoniak , Carlo Bieńkowski , Dominik Bursa , Agata Skrzat-Klapaczyńska , Svitlana Antonyak , Larisa Hetman , Olga Gvozdetska

{"title":"Continuity of HIV and hepatitis C care in times of war – Five Times Ninety project","authors":"Justyna D. Kowalska , Bartłomiej Matłosz , Olena Samsonova , Sergii Antoniak , Carlo Bieńkowski , Dominik Bursa , Agata Skrzat-Klapaczyńska , Svitlana Antonyak , Larisa Hetman , Olga Gvozdetska","doi":"10.1016/j.jiph.2025.102950","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Five Times Ninety project investigates the utility of “Standardized protocol for clinical management and medical data sharing for PLHIV among refugees from Ukraine”.</div></div><div><h3>Methods</h3><div>Refugees who registered to HIV care in Warsaw were followed according to the protocol. For each person data were linked to Public Health Center Ministry of Health Ukraine and sent back on standardized form. Data were censored at 31.12.2023. Analyses were performer using Rv. 4.4.1 software.</div></div><div><h3>Results</h3><div>Of 205 refugees, who registered to HIV care in Warsaw 202 (98.7 %) were linked with PHC database; 121 (59.9 %) were female, median age was 40.0 (IQR 36.0–46.0), migrating mainly from Central Ukraine (67; 33.2 %), diagnosed with HIV between 1996 and 2022 and 52 (25.9 %) persons ever diagnosed with All patients were on ART: 167 (84.8 %) on dolutegravir one tablet regimen and 178 (90.8 %) had HIV viral load < 50 copies/ml on last measurement in Ukraine. Most refugees (128; 63.4 %) remained in care with 179 (88.6 %) having two, 159 (78.7 %) having three, 139 (68.8 %) having four, 107 (53.0 %) having five visits. Of 59 (31.5 %) tested positive for HCV serology in Poland, 24 were already treated in Ukraine, 25 had detectable HCV RNA and 10 received therapy in Poland</div></div><div><h3>Conclusions</h3><div>The protocol is an efficient tool for medical data exchange in the forced migration settings. Viral suppression among Ukrainian refugees on ART decreased but remained high and improving with time. Routine HCV screening is necessary, as large proportion of this population was not screened and many of them require treatment.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 12","pages":"Article 102950"},"PeriodicalIF":4.0000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Infection and Public Health","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1876034125002990","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Five Times Ninety project investigates the utility of “Standardized protocol for clinical management and medical data sharing for PLHIV among refugees from Ukraine”.

Methods

Refugees who registered to HIV care in Warsaw were followed according to the protocol. For each person data were linked to Public Health Center Ministry of Health Ukraine and sent back on standardized form. Data were censored at 31.12.2023. Analyses were performer using Rv. 4.4.1 software.

Results

Of 205 refugees, who registered to HIV care in Warsaw 202 (98.7 %) were linked with PHC database; 121 (59.9 %) were female, median age was 40.0 (IQR 36.0–46.0), migrating mainly from Central Ukraine (67; 33.2 %), diagnosed with HIV between 1996 and 2022 and 52 (25.9 %) persons ever diagnosed with All patients were on ART: 167 (84.8 %) on dolutegravir one tablet regimen and 178 (90.8 %) had HIV viral load < 50 copies/ml on last measurement in Ukraine. Most refugees (128; 63.4 %) remained in care with 179 (88.6 %) having two, 159 (78.7 %) having three, 139 (68.8 %) having four, 107 (53.0 %) having five visits. Of 59 (31.5 %) tested positive for HCV serology in Poland, 24 were already treated in Ukraine, 25 had detectable HCV RNA and 10 received therapy in Poland

Conclusions

The protocol is an efficient tool for medical data exchange in the forced migration settings. Viral suppression among Ukrainian refugees on ART decreased but remained high and improving with time. Routine HCV screening is necessary, as large proportion of this population was not screened and many of them require treatment.

查看原文本刊更多论文

战争时期艾滋病毒和丙型肝炎护理的连续性-五倍九十项目

“五倍九十”项目调查了“乌克兰难民艾滋病病毒临床管理和医疗数据共享标准化协议”的效用。方法对在华沙登记参加艾滋病护理的难民按照方案进行随访。每个人的数据都与乌克兰卫生部公共卫生中心联系起来，并以标准化形式发回。数据在2023年12月31日进行了审查。采用Rv. 4.4.1软件进行分析。结果在华沙登记参加艾滋病毒护理的205名难民中，202名（98.7 %）与PHC数据库连接；121例（59.9 %）为女性，年龄中位数为40.0 (IQR为36.0-46.0)，主要来自乌克兰中部（67;33.2% %），在1996年至2022年间被诊断为艾滋病毒，52例（25.9 %）曾被诊断为艾滋病毒。所有患者均接受抗逆转录病毒治疗：167例（84.8 %）接受多鲁替韦单片方案治疗，178例（90.8 %）在乌克兰的HIV病毒载量为 50拷贝/ml。大多数难民（128人，63.4 %）仍然得到照顾，179人（88.6% %）得到两次照顾，159人（78.7% %）得到三次照顾，139人（68.8% %）得到四次照顾，107人（53.0% %）得到五次照顾。在波兰，59例（31.5 %）HCV血清学检测呈阳性，其中24例已在乌克兰接受治疗，25例检测到HCV RNA， 10例在波兰接受治疗。结论：该方案是强制迁移环境中医疗数据交换的有效工具。在接受抗逆转录病毒治疗的乌克兰难民中，病毒抑制程度有所下降，但仍然很高，并随着时间的推移而改善。常规丙型肝炎病毒筛查是必要的，因为这一人群中有很大一部分没有接受筛查，其中许多人需要治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Infection and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -INFECTIOUS DISEASES

CiteScore

13.10

自引率

1.50%

发文量

203

审稿时长

96 days

期刊介绍： The Journal of Infection and Public Health, first official journal of the Saudi Arabian Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences and the Saudi Association for Public Health, aims to be the foremost scientific, peer-reviewed journal encompassing infection prevention and control, microbiology, infectious diseases, public health and the application of healthcare epidemiology to the evaluation of health outcomes. The point of view of the journal is that infection and public health are closely intertwined and that advances in one area will have positive consequences on the other. The journal will be useful to all health professionals who are partners in the management of patients with communicable diseases, keeping them up to date. The journal is proud to have an international and diverse editorial board that will assist and facilitate the publication of articles that reflect a global view on infection control and public health, as well as emphasizing our focus on supporting the needs of public health practitioners. It is our aim to improve healthcare by reducing risk of infection and related adverse outcomes by critical review, selection, and dissemination of new and relevant information in the field of infection control, public health and infectious diseases in all healthcare settings and the community.