Ectopic thyroid tissue in the mandible: Case report

IF 0.5 Q4 Medicine

Revista Espanola de Patologia Pub Date : 2025-09-10 DOI:10.1016/j.patol.2025.100842

Daniela Alejandra García Alonso , Moisés Salamanca García , María Edith Salgado Alday

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Abstract

Background

Ectopic thyroid tissue is a rare condition, with an estimated prevalence of 1 case per 300,000 individuals. The lingual region is the most common site of ectopia. To date, only two cases of ectopic thyroid tissue in the mandibular bone have been reported.

Clinical case

A 62-year-old woman presented with oedema and pain in the lower left second molar, which had progressively worsened and did not improve despite analgesic treatment. As an initial diagnostic approach, an orthopantomogram was performed, revealing extensive destruction of the left mandible. A biopsy of the affected area was subsequently obtained. Histological examination identified thyroid tissue within the bone trabeculae, consisting of thyroid follicles with colloid content.

Conclusion

The diagnosis of ectopic thyroid is uncommon and often challenging to establish. It is therefore essential to be aware of the various clinical manifestations and possible locations of ectopia in order to achieve accurate diagnosis and appropriate treatment.

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下颌骨甲状腺组织异位1例

背景：甲状腺组织异位是一种罕见的疾病，估计患病率为每30万人中有1例。舌区是最常见的异位部位。迄今为止，只有两例异位甲状腺组织在下颌骨已被报道。临床病例：一名62岁女性，左下第二磨牙水肿和疼痛，病情逐渐恶化，尽管进行了镇痛治疗，但仍未好转。作为最初的诊断方法，进行了骨断层扫描，发现左下颌骨大面积破坏。随后对患处进行活组织检查。组织学检查发现骨小梁内的甲状腺组织，由含有胶体的甲状腺滤泡组成。结论异位甲状腺的诊断并不常见，且往往难以确定。因此，了解异位的各种临床表现和可能的位置，以达到准确的诊断和适当的治疗是至关重要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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