{"title":"Maternal and foetal outcomes of scrub typhus in pregnancy: A retrospective study.","authors":"Nilofer A Rajasab, Syed Ahmed Zaki","doi":"10.1177/00494755251376113","DOIUrl":null,"url":null,"abstract":"<p><p>Scrub typhus, caused by <i>Orientia tsutsugamushi</i>, is a zoonotic infection endemic to the Asia-Pacific region. Its severity ranges from mild illness to life-threatening complications and case fatality rate upto 30%, highlighting the importance of early diagnosis. This study analyzed the clinical profile and pregnancy outcomes of 34 pregnant women diagnosed with scrub typhus at a tertiary care and referral centre. Poor foetal outcomes were observed in 18 (53%) pregnancies with intra-uterine deaths and spontaneous abortion occurring in 12 cases, while six had preterm births between 32 and 35 weeks of gestation. There was no maternal mortality. In endemic regions, scrub typhus should be considered in all pregnant women presenting with unexplained fever. Early diagnosis and prompt treatment are crucial to improving maternal and foetal outcomes.</p>","PeriodicalId":49415,"journal":{"name":"Tropical Doctor","volume":" ","pages":"494755251376113"},"PeriodicalIF":0.6000,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tropical Doctor","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00494755251376113","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Scrub typhus, caused by Orientia tsutsugamushi, is a zoonotic infection endemic to the Asia-Pacific region. Its severity ranges from mild illness to life-threatening complications and case fatality rate upto 30%, highlighting the importance of early diagnosis. This study analyzed the clinical profile and pregnancy outcomes of 34 pregnant women diagnosed with scrub typhus at a tertiary care and referral centre. Poor foetal outcomes were observed in 18 (53%) pregnancies with intra-uterine deaths and spontaneous abortion occurring in 12 cases, while six had preterm births between 32 and 35 weeks of gestation. There was no maternal mortality. In endemic regions, scrub typhus should be considered in all pregnant women presenting with unexplained fever. Early diagnosis and prompt treatment are crucial to improving maternal and foetal outcomes.
期刊介绍：
The only journal written by and for health workers in low and middle-income countries, Tropical Doctor provides medical expertise and practical advice on how to apply current medical knowledge to the special circumstances of LMIC countries. This journal provides an ideal forum for sharing experiences and establishing best practice, aiding communication between medical professionals in different environments.
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