Effects of Aerobic Exercises at Different Intensities on Sleep Quality in Individuals with Depression: A Systematic Review and Meta-Analysis.

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Nature and Science of Sleep Pub Date : 2025-09-03 eCollection Date: 2025-01-01 DOI:10.2147/NSS.S520079

Jiaqi Liang, Xuanzhen Pan, Li Zhao, Yan Li

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引用次数: 0

Abstract

Purpose: Depression patients frequently report sleep disorder. Aerobic exercise is believed to improve sleep quality, but its effect on the overall sleep of depressed patients remains uncertain. This study systematically evaluates the effects of aerobic exercises at different intensities on subjective and objective sleep quality in participants diagnosed with depression or at high risk of depression, from studies covering various depression subtypes (including but not limited to geriatric depression, prenatal depression, and poststroke depression), and examines changes in depression, anxiety, and quality of life following aerobic exercise.

Methods: Systematic searches for randomized controlled trials on aerobic exercise, depression, and sleep quality were conducted using PubMed, Web of Science, Embase, and the Cochrane Library up to December 31, 2024. Meta-analysis was performed using Review Manager 5.4.1 and stata 17.0.

Results: In total, 13 trials (n = 994) were included. Aerobic exercise significantly improved subjective sleep quality [SMD = -0.52, 95% CI = (-0.66, -0.38)] but had no significant effect on objectively measured sleep efficiency [SMD = -0.14, 95% CI = (-0.46, 0.75)], total sleep time [SMD = 0.30, 95% CI = (-0.03, 0.62)], or sleep latency [SMD = -0.11, 95% CI = (-0.76, 0.54)]. Additionally, aerobic exercise significantly alleviated depression [SMD = -0.70, 95% CI = (-0.93, -0.47)] and anxiety [SMD = -0.47, 95% CI = (-0.74, -0.19)], and enhanced quality of life [SMD = 0.64, 95% CI = (0.36, 0.92)]. Subgroup analyses revealed no significant differences among the different intensities.

Conclusion: Aerobic exercise significantly improves subjective sleep quality, alleviates depressive and anxiety symptoms, and enhances quality of life in depression patients. Light-, moderate-, and vigorous-intensities aerobic exercises have equal positive effects on these indicators. Given the bidirectional relationship between sleep disturbances and depression progression, this study highlights the potential of exercise therapy to disrupt the vicious cycle.

Systematic review registration: www.crd.york.ac.uk/PROSPERO/, identifier, CRD42023455212.

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不同强度有氧运动对抑郁症患者睡眠质量的影响：一项系统综述和荟萃分析。

目的：抑郁症患者经常报告睡眠障碍。有氧运动被认为可以改善睡眠质量，但它对抑郁症患者整体睡眠的影响仍不确定。本研究系统地评估了不同强度的有氧运动对诊断为抑郁症或抑郁症高风险参与者主观和客观睡眠质量的影响，研究涵盖了各种抑郁症亚型（包括但不限于老年抑郁症、产前抑郁症和中风后抑郁症），并检查了有氧运动后抑郁、焦虑和生活质量的变化。方法：系统检索截至2024年12月31日的PubMed、Web of Science、Embase和Cochrane Library中关于有氧运动、抑郁和睡眠质量的随机对照试验。meta分析采用Review Manager 5.4.1和stata 17.0进行。结果：共纳入13项试验（n = 994）。有氧运动显著改善了主观睡眠质量[SMD = -0.52, 95% CI =(-0.66, -0.38)]，但对客观测量的睡眠效率[SMD = -0.14, 95% CI =(-0.46, 0.75)]、总睡眠时间[SMD = 0.30, 95% CI =(-0.03, 0.62)]或睡眠潜伏期[SMD = -0.11, 95% CI =(-0.76, 0.54)]没有显著影响。此外，有氧运动显著缓解抑郁[SMD = -0.70, 95% CI =(-0.93, -0.47)]和焦虑[SMD = -0.47, 95% CI =(-0.74, -0.19)]，提高生活质量[SMD = 0.64, 95% CI =(0.36, 0.92)]。亚组分析显示不同强度间无显著差异。结论：有氧运动可显著改善抑郁症患者主观睡眠质量，减轻抑郁、焦虑症状，提高生活质量。轻强度、中等强度和高强度有氧运动对这些指标有同样的积极影响。考虑到睡眠障碍和抑郁症进展之间的双向关系，这项研究强调了运动疗法打破恶性循环的潜力。系统评审注册：www.crd.york.ac.uk/PROSPERO/，标识符，CRD42023455212。

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来源期刊

Nature and Science of Sleep Neuroscience-Behavioral Neuroscience

CiteScore

5.70

自引率

5.90%

发文量

245

审稿时长

16 weeks

期刊介绍： Nature and Science of Sleep is an international, peer-reviewed, open access journal covering all aspects of sleep science and sleep medicine, including the neurophysiology and functions of sleep, the genetics of sleep, sleep and society, biological rhythms, dreaming, sleep disorders and therapy, and strategies to optimize healthy sleep. Specific topics covered in the journal include: The functions of sleep in humans and other animals Physiological and neurophysiological changes with sleep The genetics of sleep and sleep differences The neurotransmitters, receptors and pathways involved in controlling both sleep and wakefulness Behavioral and pharmacological interventions aimed at improving sleep, and improving wakefulness Sleep changes with development and with age Sleep and reproduction (e.g., changes across the menstrual cycle, with pregnancy and menopause) The science and nature of dreams Sleep disorders Impact of sleep and sleep disorders on health, daytime function and quality of life Sleep problems secondary to clinical disorders Interaction of society with sleep (e.g., consequences of shift work, occupational health, public health) The microbiome and sleep Chronotherapy Impact of circadian rhythms on sleep, physiology, cognition and health Mechanisms controlling circadian rhythms, centrally and peripherally Impact of circadian rhythm disruptions (including night shift work, jet lag and social jet lag) on sleep, physiology, cognition and health Behavioral and pharmacological interventions aimed at reducing adverse effects of circadian-related sleep disruption Assessment of technologies and biomarkers for measuring sleep and/or circadian rhythms Epigenetic markers of sleep or circadian disruption.