Full Free-Breathing Cardiac MRI: Enhancing Efficiency and Image Quality in Clinical Practice.

IF 6.1 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Kai Yang, Chen Cui, Fei Teng, Gang Yin, Jing An, Xinling Yang, Jinghui Li, Xiaoming Bi, Jianing Pang, Kelvin Chow, Shihua Zhao, Minjie Lu
{"title":"Full Free-Breathing Cardiac MRI: Enhancing Efficiency and Image Quality in Clinical Practice.","authors":"Kai Yang, Chen Cui, Fei Teng, Gang Yin, Jing An, Xinling Yang, Jinghui Li, Xiaoming Bi, Jianing Pang, Kelvin Chow, Shihua Zhao, Minjie Lu","doi":"10.1016/j.jocmr.2025.101955","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Conventional cardiac magnetic resonance (CMR) examinations require patients to repeatedly hold their breath, which can reduce examination efficiency and pose challenges for patients unable to do so. This study aimed to demonstrate the feasibility and effectiveness of a full free-breathing CMR protocol in clinical practice.</p><p><strong>Methods: </strong>Patients prospectively enrolled in this study underwent a full free-breathing CMR exam on a 3T scanner between June 1 and June 30, 2024. Acquisition time and image quality were assessed. Cine and flow imaging were compared with those acquired with the conventional breath-holding CMR protocol. Other sequences, including T1/T2 mapping and late gadolinium enhancement (LGE), were evaluated quantitatively and qualitatively, respectively. Group comparisons were performed using the Wilcoxon signed-rank test or paired t-test. Consistency was assessed using Kappa statistics, Bland-Altman statistics, intraclass correlation coefficient (ICC) and linear regression.</p><p><strong>Results: </strong>A total of 211 patients were evaluated (median age: 53 years [IQR: 38-63]; range: 10-82 years; 145 men). The mean acquisition time for full free-breathing CMR was 22.6±3.7min. The median image quality scores for cine and LGE images acquired with free-breathing CMR were 4 (IQR: 4-4) and 5 (IQR: 4-5), respectively. Compared with conventional breath-holding CMR, the end-diastolic volume (EDV), end-systolic volume (ESV), EDV index and ESV index measured by free-breathing CMR were slightly higher (all P<0.05), whereas the left ventricular ejection fraction (LVEF) and left ventricular mass (LVM) were slightly lower (both P<0.05). Nonetheless, the two methods demonstrated good agreement and correlation (r values: 0.85-0.99). Native T1 and T2 values in healthy subjects from free-breathing CMR were 1214.9±16.7ms and 38.4±3.2ms, respectively. Among the 211 patients, 147 were LGE positive. Except for five patients with image quality scores below 3, all others had scores of 3 or higher.</p><p><strong>Conclusion: </strong>Full free-breathing CMR examinations are feasible and effective in clinical practice, significantly reduce scan time while maintaining high image quality.</p>","PeriodicalId":15221,"journal":{"name":"Journal of Cardiovascular Magnetic Resonance","volume":" ","pages":"101955"},"PeriodicalIF":6.1000,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cardiovascular Magnetic Resonance","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jocmr.2025.101955","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Conventional cardiac magnetic resonance (CMR) examinations require patients to repeatedly hold their breath, which can reduce examination efficiency and pose challenges for patients unable to do so. This study aimed to demonstrate the feasibility and effectiveness of a full free-breathing CMR protocol in clinical practice.

Methods: Patients prospectively enrolled in this study underwent a full free-breathing CMR exam on a 3T scanner between June 1 and June 30, 2024. Acquisition time and image quality were assessed. Cine and flow imaging were compared with those acquired with the conventional breath-holding CMR protocol. Other sequences, including T1/T2 mapping and late gadolinium enhancement (LGE), were evaluated quantitatively and qualitatively, respectively. Group comparisons were performed using the Wilcoxon signed-rank test or paired t-test. Consistency was assessed using Kappa statistics, Bland-Altman statistics, intraclass correlation coefficient (ICC) and linear regression.

Results: A total of 211 patients were evaluated (median age: 53 years [IQR: 38-63]; range: 10-82 years; 145 men). The mean acquisition time for full free-breathing CMR was 22.6±3.7min. The median image quality scores for cine and LGE images acquired with free-breathing CMR were 4 (IQR: 4-4) and 5 (IQR: 4-5), respectively. Compared with conventional breath-holding CMR, the end-diastolic volume (EDV), end-systolic volume (ESV), EDV index and ESV index measured by free-breathing CMR were slightly higher (all P<0.05), whereas the left ventricular ejection fraction (LVEF) and left ventricular mass (LVM) were slightly lower (both P<0.05). Nonetheless, the two methods demonstrated good agreement and correlation (r values: 0.85-0.99). Native T1 and T2 values in healthy subjects from free-breathing CMR were 1214.9±16.7ms and 38.4±3.2ms, respectively. Among the 211 patients, 147 were LGE positive. Except for five patients with image quality scores below 3, all others had scores of 3 or higher.

Conclusion: Full free-breathing CMR examinations are feasible and effective in clinical practice, significantly reduce scan time while maintaining high image quality.

全自由呼吸心脏MRI:提高临床实践的效率和图像质量。
背景:传统的心脏磁共振(CMR)检查需要患者反复屏气,这降低了检查效率,对无法屏气的患者构成了挑战。本研究旨在证明完全自由呼吸CMR方案在临床实践中的可行性和有效性。方法:在2024年6月1日至6月30日期间,前瞻性纳入本研究的患者在3T扫描仪上进行了完全自由呼吸CMR检查。评估了采集时间和图像质量。将常规屏气CMR方案获得的影像与血流成像进行比较。其他序列,包括T1/T2定位和晚期钆增强(LGE),分别进行了定量和定性评价。采用Wilcoxon符号秩检验或配对t检验进行组间比较。一致性评估采用Kappa统计、Bland-Altman统计、类内相关系数(ICC)和线性回归。结果:共评估211例患者(中位年龄:53岁[IQR: 38-63];范围:10-82岁;男性145例)。全自由呼吸CMR平均采集时间为22.6±3.7min。自由呼吸CMR获得的电影和LGE图像质量得分中位数分别为4 (IQR: 4-4)和5 (IQR: 4-5)。与常规憋气CMR相比,自由呼吸CMR测量的舒张末期容积(EDV)、收缩末期容积(ESV)、EDV指数和ESV指数均略高(P<0.05),左室射血分数(LVEF)和左室质量(LVM)均略低(P<0.05)。尽管如此,两种方法显示出良好的一致性和相关性(r值:0.85-0.99)。健康受试者自由呼吸CMR的T1和T2值分别为1214.9±16.7ms和38.4±3.2ms。211例患者中LGE阳性147例。除5例图像质量评分低于3分外,其余均在3分及以上。结论:全自由呼吸CMR检查在临床实践中是可行和有效的,在保持高图像质量的同时显著缩短了扫描时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
10.90
自引率
12.50%
发文量
61
审稿时长
6-12 weeks
期刊介绍: Journal of Cardiovascular Magnetic Resonance (JCMR) publishes high-quality articles on all aspects of basic, translational and clinical research on the design, development, manufacture, and evaluation of cardiovascular magnetic resonance (CMR) methods applied to the cardiovascular system. Topical areas include, but are not limited to: New applications of magnetic resonance to improve the diagnostic strategies, risk stratification, characterization and management of diseases affecting the cardiovascular system. New methods to enhance or accelerate image acquisition and data analysis. Results of multicenter, or larger single-center studies that provide insight into the utility of CMR. Basic biological perceptions derived by CMR methods.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信