Global, regional and national burdens of mental disorders, substance use disorders and self-harm among adolescents and young adults, 1990-2021: a systematic analysis for the Global Burden of Diseases Study 2021.

IF 3.7 3区 医学 Q1 CLINICAL NEUROLOGY
Siwei Sun, Qiqi Chen, Guoping Li, Hui Yang, Wenqing Cai, Yunning Hu, Yuxi Zhang, Xin Yang, Yan Liu, Le Zhang, Kai Yuan, Yang Deng
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Abstract

Concerns over the mental health among young people have been increasing recently. We aimed to estimate the burdens of mental disorders, substance use disorders (SUDs), and self-harm at global, regional and national levels among adolescents and young adults aged 10-24 years from 1990 to 2021. Incidence, prevalence, and disability-adjusted life years (DALYs) of mental disorders, SUDs, and self-harm among young people were examined by age, sex, region, and country/territory. Average annual percentage changes (AAPCs) were utilized to assess the temporal trends of age-standardized rates during 1990-2021. Spearman rank-correlation analysis was used to analyze the correlation between age-standardized rates for incidence, prevalence, and DALYs and Socio-demographic Index (SDI). In 2021, there were 36.32 million DALYs due to mental disorders, 4.37 million DALYs due to SUDs, and 8.00 million DALYs due to self-harm among adolescents and young adults aged 10-24 years globally. Age-standardized DALY rate of mental disorders exhibited a slightly increasing trend, whereas DALY rates of SUDs and self-harm decreased from 1990 to 2021. Age-standardized incidence, prevalence, and DALY rates for depressive and anxiety disorders in 2020 and 2021 were approximately 20% higher than those observed in the pre-pandemic period. The burdens of mental disorders, SUDs, and self-harm were higher in high SDI countries such as New Zealand, Australia, Greenland, United States of America, and Canada. Global burdens due to mental disorders, mainly included anxiety and depressive disorders among adolescents and young adults markedly increased from 1990 to 2021, with a significant increase coinciding with the COVID-19 pandemic.

1990-2021年青少年和年轻人精神障碍、物质使用障碍和自我伤害的全球、区域和国家负担:对《2021年全球疾病负担研究》的系统分析。
最近,人们越来越关注年轻人的心理健康。我们的目的是估计1990年至2021年全球、区域和国家层面10-24岁青少年和年轻人的精神障碍、物质使用障碍(sud)和自残负担。按年龄、性别、地区和国家/地区检查年轻人中精神障碍、sud和自残的发病率、流行率和残疾调整生命年(DALYs)。使用平均年百分比变化(AAPCs)评估1990-2021年年龄标准化率的时间趋势。采用Spearman秩相关分析分析年龄标准化发生率、患病率、DALYs与社会人口指数(SDI)之间的相关性。2021年,全球10-24岁的青少年和年轻人中,因精神障碍导致的伤残调整生命年为3632万,因SUDs导致的伤残调整生命年为437万,因自残导致的伤残调整生命年为800万。1990 - 2021年,精神障碍的年龄标准化DALY率呈轻微上升趋势,而猝死和自残的DALY率呈下降趋势。2020年和2021年,抑郁症和焦虑症的年龄标准化发病率、流行率和伤残调整年率比大流行前时期高约20%。精神障碍、sud和自残的负担在高SDI国家如新西兰、澳大利亚、格陵兰、美利坚合众国和加拿大更高。从1990年到2021年,全球青少年和青壮年因精神障碍造成的负担(主要包括焦虑和抑郁障碍)显著增加,与COVID-19大流行同期显著增加。
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来源期刊
CiteScore
8.80
自引率
4.30%
发文量
154
审稿时长
6-12 weeks
期刊介绍: The original papers published in the European Archives of Psychiatry and Clinical Neuroscience deal with all aspects of psychiatry and related clinical neuroscience. Clinical psychiatry, psychopathology, epidemiology as well as brain imaging, neuropathological, neurophysiological, neurochemical and moleculargenetic studies of psychiatric disorders are among the topics covered. Thus both the clinician and the neuroscientist are provided with a handy source of information on important scientific developments.
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