Sparganum-Induced Eosinophilic Pleural Effusion: a Case Report Emphasizing Laboratory Diagnostic Strategies.

IF 0.6 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Clinical laboratory Pub Date : 2025-09-01 DOI:10.7754/Clin.Lab.2025.250358

Chunxiao He, Qing Wang, Xiuping Xu

{"title":"Sparganum-Induced Eosinophilic Pleural Effusion: a Case Report Emphasizing Laboratory Diagnostic Strategies.","authors":"Chunxiao He, Qing Wang, Xiuping Xu","doi":"10.7754/Clin.Lab.2025.250358","DOIUrl":null,"url":null,"abstract":"Background: Eosinophilic pleural effusion (EPE), characterized by atypical symptoms and rarity, is easily over-looked and misdiagnosed.Methods: The patient underwent comprehensive routine laboratory tests including blood analysis and pleural effusion examination, along with B-ultrasound and computed tomography (CT) imaging. Based on combined evaluation of the epidemiological history, serum-specific parasite antibody detection and targeted Next-Generation Sequencing were performed on the clinical specimens.Results: The blood routine and pleural fluid routine of the patients suggested that the eosinophils were significantly increased. The serum-specific parasite antibody detection showed positive sparganosis antibody. Based on the diagnosis of sparganosis for this patient, he was treated with praziquantel and pleural effusion drainage, and the symptoms improved significantly.Conclusions: The etiological diagnosis of EPE is challenging and requires a comprehensive evaluation of clinical symptoms, epidemiological history, and laboratory test results. When parasitic pleural effusion is strongly suspected, tests such as serum-specific parasite antibody detection can aid in confirming the diagnosis.","PeriodicalId":10384,"journal":{"name":"Clinical laboratory","volume":"71 9","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical laboratory","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.7754/Clin.Lab.2025.250358","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Eosinophilic pleural effusion (EPE), characterized by atypical symptoms and rarity, is easily over-looked and misdiagnosed.

Methods: The patient underwent comprehensive routine laboratory tests including blood analysis and pleural effusion examination, along with B-ultrasound and computed tomography (CT) imaging. Based on combined evaluation of the epidemiological history, serum-specific parasite antibody detection and targeted Next-Generation Sequencing were performed on the clinical specimens.

Results: The blood routine and pleural fluid routine of the patients suggested that the eosinophils were significantly increased. The serum-specific parasite antibody detection showed positive sparganosis antibody. Based on the diagnosis of sparganosis for this patient, he was treated with praziquantel and pleural effusion drainage, and the symptoms improved significantly.

Conclusions: The etiological diagnosis of EPE is challenging and requires a comprehensive evaluation of clinical symptoms, epidemiological history, and laboratory test results. When parasitic pleural effusion is strongly suspected, tests such as serum-specific parasite antibody detection can aid in confirming the diagnosis.

查看原文本刊更多论文

spargins诱导的嗜酸性胸腔积液：一个强调实验室诊断策略的病例报告。

背景：嗜酸性胸腔积液（EPE）症状不典型且罕见，容易被忽视和误诊。方法：对患者进行了全面的常规实验室检查，包括血液分析和胸腔积液检查，以及b超和计算机断层扫描（CT）成像。结合流行病学史评估，对临床标本进行血清特异性寄生虫抗体检测和靶向新一代测序。结果：患者血常规及胸水常规均提示嗜酸性粒细胞明显升高。血清特异性寄生虫抗体检测为斯巴达病抗体阳性。根据该患者的斯巴达病诊断，给予吡喹酮和胸腔积液引流治疗，症状明显改善。结论：EPE的病因诊断具有挑战性，需要对临床症状、流行病学史和实验室检测结果进行综合评估。当强烈怀疑有寄生性胸腔积液时，血清特异性寄生虫抗体检测等检查可有助于确诊。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical laboratory 医学-医学实验技术

CiteScore

1.50

自引率

0.00%

发文量

494

审稿时长

3 months

期刊介绍： Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.