A Rare Case of Kikuchi-Fujimoto Disease Complicated with Hemophagocytic Lymphohistiocytosis.

IF 0.6 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Clinical laboratory Pub Date : 2025-09-01 DOI:10.7754/Clin.Lab.2025.250227

Yingying Sun, Chengcheng Wu, Chunyan Liu, Zonghong Shao

引用次数: 0

Abstract

Background: Kikuchi-Fujimoto disease (KFD) is a benign, self-limited, rare disease that rarely coexists with hemophagocytic lymphohistiocytosis (HLH).

Methods: We reported a case of a young female who presented with recurrent fever accompanied by painful lymphadenopathy, joint pain, and skin rash.

Results: Excisional biopsy of lymph node indicated KFD. The clinical symptoms, along with the laboratory findings met the diagnostic criteria for HLH. The patient recovered after receiving glucocorticoid and supportive care.

Conclusions: The combination of KFD and HLH exhibits distinct clinical characteristics and prognosis. Clinicians should be aware of this condition and avoid inappropriate diagnostic and therapeutic interventions.

查看原文本刊更多论文

罕见的菊池-藤本病合并噬血细胞性淋巴组织细胞增多症1例。

背景：Kikuchi-Fujimoto病（KFD）是一种良性、自限性、罕见的疾病，很少与噬血细胞性淋巴组织细胞增多症（HLH）共存。方法：我们报告了一例年轻女性，她表现为反复发烧，伴有疼痛的淋巴结病，关节痛和皮疹。结果：淋巴结切除活检提示KFD。临床症状和实验室结果符合HLH的诊断标准。患者在接受糖皮质激素治疗和支持性护理后康复。结论：KFD合并HLH具有明显的临床特点和预后。临床医生应该意识到这种情况，避免不适当的诊断和治疗干预。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical laboratory 医学-医学实验技术

CiteScore

1.50

自引率

0.00%

发文量

494

审稿时长

3 months

期刊介绍： Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.