Zeynep Yegin Katran, İsmet Bulut, Feyza Yegin, Mustafa Katran
{"title":"A practical and applicable desensitization scheme for ciprofloxacin with a glass of water.","authors":"Zeynep Yegin Katran, İsmet Bulut, Feyza Yegin, Mustafa Katran","doi":"10.15586/aei.v53i5.1413","DOIUrl":null,"url":null,"abstract":"<p><p>Desensitization is an immunological process that creates temporary tolerance to a drug, which disappears once treatment is discontinued. Ciprofloxacin is a commonly used antibiotic, particularly for chronic lung diseases, yet there are very few desensitization protocols for it. Two ciprofloxacin desensitization schemes were developed a long time ago. However, these protocols are multistep, time-consuming processes, due to which a new protocol is required. We would like to present the practical oral desensitization protocol that we use. We included two patients with cystic fibrosis and bronchiectasis who required ciprofloxacin due to the presence of <i>Pseudomonas aeruginosa</i> in their sputum cultures. The desensitization process was successful and well-tolerated. This protocol is important because it addresses a significant gap in the literature.</p>","PeriodicalId":7536,"journal":{"name":"Allergologia et immunopathologia","volume":"53 5","pages":"135-137"},"PeriodicalIF":2.1000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Allergologia et immunopathologia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.15586/aei.v53i5.1413","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"ALLERGY","Score":null,"Total":0}
引用次数: 0
Abstract
Desensitization is an immunological process that creates temporary tolerance to a drug, which disappears once treatment is discontinued. Ciprofloxacin is a commonly used antibiotic, particularly for chronic lung diseases, yet there are very few desensitization protocols for it. Two ciprofloxacin desensitization schemes were developed a long time ago. However, these protocols are multistep, time-consuming processes, due to which a new protocol is required. We would like to present the practical oral desensitization protocol that we use. We included two patients with cystic fibrosis and bronchiectasis who required ciprofloxacin due to the presence of Pseudomonas aeruginosa in their sputum cultures. The desensitization process was successful and well-tolerated. This protocol is important because it addresses a significant gap in the literature.
期刊介绍：
Founded in 1972 by Professor A. Oehling, Allergologia et Immunopathologia is a forum for those working in the field of pediatric asthma, allergy and immunology. Manuscripts related to clinical, epidemiological and experimental allergy and immunopathology related to childhood will be considered for publication. Allergologia et Immunopathologia is the official journal of the Spanish Society of Pediatric Allergy and Clinical Immunology (SEICAP) and also of the Latin American Society of Immunodeficiencies (LASID). It has and independent international Editorial Committee which submits received papers for peer-reviewing by international experts. The journal accepts original and review articles from all over the world, together with consensus statements from the aforementioned societies. Occasionally, the opinion of an expert on a burning topic is published in the "Point of View" section. Letters to the Editor on previously published papers are welcomed. Allergologia et Immunopathologia publishes 6 issues per year and is included in the major databases such as Pubmed, Scopus, Web of Knowledge, etc.
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