Proactive Cognitive Stimulation for Younger Adults With Down Syndrome. A Feasibility Randomised Control Trial

IF 1.9 3区医学 Q2 PSYCHOLOGY, EDUCATIONAL

Journal of Applied Research in Intellectual Disabilities Pub Date : 2025-09-10 DOI:10.1111/jar.70120

Sharon Hardiman, Rory Cousins, Aisling Ryan, Maria Kennedy, Leigh Hagan, Flavia H. Santos

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引用次数: 0

Abstract

Background

Most adults with Down syndrome develop Alzheimer's disease (AD) pathology in their 30s, yet research into cognitive health programmes for this group remains limited.

Method

A mixed-methods feasibility randomised control trial (RCT) evaluated an adapted, manualised group-based cognitive stimulation therapy (CST) programme for adults with Down syndrome (N = 12; M_age = 30) without dementia. Participants were randomly assigned to CST (n = 6) or control (services as usual; n = 6), with assessments at baseline, post-programme, and four-month follow-up by a blinded researcher.

Results

The adapted CST was feasible, with high attendance, strong satisfaction, and good CST programme fidelity (all > 85%). CST participants showed significant gains in adaptive behaviour at post-programme, maintained at follow-up, and a trend towards improved episodic memory at post-programme.

Conclusion

Manualised group-based CST can be successfully adapted for younger adults with Down syndrome and shows promise in supporting cognitive health for this population.

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主动认知刺激治疗年轻唐氏综合症。可行性随机对照试验

大多数患有唐氏综合症的成年人在30多岁时出现阿尔茨海默病（AD）病理，但对这一群体的认知健康计划的研究仍然有限。方法一项混合方法可行性随机对照试验（RCT）评估了一种适应的、手动的基于群体的认知刺激疗法（CST）方案，用于治疗无痴呆的成人唐氏综合征（N = 12; Mage = 30）。参与者被随机分配到CST组（n = 6）或对照组（照常服务；n = 6），由盲法研究人员在基线、方案后和4个月的随访中进行评估。结果调整后的CST是可行的，有较高的出勤率、较高的满意度和良好的CST节目保真度（均为85%）。CST参与者在节目后的适应性行为方面表现出显著的进步，在随访中保持不变，并且在节目后的情景记忆方面有改善的趋势。结论手动分组CST可以成功地适用于患有唐氏综合征的年轻成人，并有望支持这一人群的认知健康。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Applied Research in Intellectual Disabilities Multiple-

CiteScore

4.70

自引率

12.50%

发文量

期刊介绍： JARID is an international, peer-reviewed journal which draws together findings derived from original applied research in intellectual disabilities. The journal is an important forum for the dissemination of ideas to promote valued lifestyles for people with intellectual disabilities. It reports on research from the UK and overseas by authors from all relevant professional disciplines. It is aimed at an international, multi-disciplinary readership. Topics covered include community living, quality of life, challenging behaviour, communication, sexuality, medication, ageing, supported employment, family issues, mental health, physical health, autism, economic issues, social networks, staff stress, staff training, epidemiology and service provision.