Unraveling the multifaceted role of C2H2-type zinc finger proteins: integrators of trichome development and abiotic stress adaptation in plants

IF 6.8 Q1 PLANT SCIENCES

Plant Stress Pub Date : 2025-08-24 DOI:10.1016/j.stress.2025.101005

Muhammad Aneeq Ur Rahman , Muhammad Ali Abid , Zoya Batool Naqvi , Mubashir Abbas , Waqas Malik , Yunxiao Wei , Rui Zhang

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引用次数: 0

Abstract

C2H2-type zinc finger proteins function as important transcriptional regulators in plants, facilitating the integration of developmental processes and environmental stress responses. This review demonstrated a comprehensive understanding of the classification, structure, and functional domains of C2H2-type zinc finger proteins, with particular emphasis on their dual roles in trichome development and abiotic stress adaptation. We described the role of C2H2-type zinc finger proteins in regulating unicellular and multicellular trichome formation in Arabidopsis and other plant species. Furthermore, the review summarized the role of these proteins in mediating plant responses to diverse abiotic stresses, including drought, oxidative, cold, heat and salinity stress. Under drought conditions, C2H2 type zinc finger proteins are known to enhance water retention and antioxidant activity; whereas during salt stress, they modulate the expression of protective genes and maintain ionic balance. Additionally, the interplay between C2H2-type zinc finger proteins and phytohormones, such as ABA and auxin, elucidated their integral role in stress signaling networks. This review explored into the molecular cross-talk between trichome development and stress response pathways, underscoring the versatility and regulatory complexity of C2H2-type zinc finger proteins. Unraveling the molecular mechanisms by which C2H2-type zinc finger proteins improve trichome development and enhance stress tolerance will facilitate the breeding and genetic engineering of crops with improved traits.

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揭示c2h2型锌指蛋白的多方面作用：植物毛状体发育和非生物胁迫适应的整合者

c2h2型锌指蛋白是植物重要的转录调控因子，促进植物发育过程和环境胁迫反应的整合。本文综述了c2h2型锌指蛋白的分类、结构和功能域，重点介绍了它们在毛状体发育和非生物胁迫适应中的双重作用。我们描述了c2h2型锌指蛋白在调节拟南芥和其他植物单细胞和多细胞毛状体形成中的作用。此外，综述了这些蛋白在介导植物对干旱、氧化、冷、热、盐胁迫等多种非生物胁迫反应中的作用。在干旱条件下，C2H2型锌指蛋白增强水分保持和抗氧化活性；而在盐胁迫下，它们调节保护基因的表达，维持离子平衡。此外，c2h2型锌指蛋白与植物激素（如ABA和生长素）之间的相互作用阐明了它们在胁迫信号网络中的重要作用。本文综述了毛状体发育与胁迫反应途径之间的分子交叉对话，强调了c2h2型锌指蛋白的多功能性和调控复杂性。揭示c2h2型锌指蛋白促进毛状体发育和增强抗逆性的分子机制，将为改良作物的育种和基因工程提供依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Plant Stress PLANT SCIENCES-

CiteScore

5.20

自引率

8.00%

发文量

审稿时长

63 days

期刊介绍： The journal Plant Stress deals with plant (or other photoautotrophs, such as algae, cyanobacteria and lichens) responses to abiotic and biotic stress factors that can result in limited growth and productivity. Such responses can be analyzed and described at a physiological, biochemical and molecular level. Experimental approaches/technologies aiming to improve growth and productivity with a potential for downstream validation under stress conditions will also be considered. Both fundamental and applied research manuscripts are welcome, provided that clear mechanistic hypotheses are made and descriptive approaches are avoided. In addition, high-quality review articles will also be considered, provided they follow a critical approach and stimulate thought for future research avenues. Plant Stress welcomes high-quality manuscripts related (but not limited) to interactions between plants and: Lack of water (drought) and excess (flooding), Salinity stress, Elevated temperature and/or low temperature (chilling and freezing), Hypoxia and/or anoxia, Mineral nutrient excess and/or deficiency, Heavy metals and/or metalloids, Plant priming (chemical, biological, physiological, nanomaterial, biostimulant) approaches for improved stress protection, Viral, phytoplasma, bacterial and fungal plant-pathogen interactions. The journal welcomes basic and applied research articles, as well as review articles and short communications. All submitted manuscripts will be subject to a thorough peer-reviewing process.