[Use of ozone therapy in the treatment of complications following penetrating keratoplasty for rosacea-associated keratitis].

Abstract

Rosacea is a chronic inflammatory dermatosis, one manifestation of which involves pathological processes in various ocular structures. The most severe form is rosacea-associated keratitis. Given the multifactorial etiology and pathogenesis, this condition remains unpredictable and resistant to treatment. This study presents a clinical case of using ozone therapy in the management of complications following penetrating keratoplasty in the setting of rosacea-associated keratitis and demonstrates the therapeutic effectiveness of ozone therapy as part of a comprehensive approach to managing post-keratoplasty complications in patients with rosacea-associated keratitis. The inclusion of ozone therapy led to clinical and functional improvement by day 10. By day 60, corneal syndrome manifestations were minimal, the graft remained transparent, and significant regression of neovascularization was observed. Due to the pronounced anti-inflammatory and reparative effects of therapeutic ozone concentrations, its use in this context is pathogenetically justified.