Septic Shock After Surgery in Arnold-Chiari Malformation Type I: A Case Report.

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL
International Medical Case Reports Journal Pub Date : 2025-08-31 eCollection Date: 2025-01-01 DOI:10.2147/IMCRJ.S543285
Roghayeh Asghari, Ata Mahmoodpoor, Fariba Pourkarim, Mostafa Ghasempour, Ramin Abri
{"title":"Septic Shock After Surgery in Arnold-Chiari Malformation Type I: A Case Report.","authors":"Roghayeh Asghari, Ata Mahmoodpoor, Fariba Pourkarim, Mostafa Ghasempour, Ramin Abri","doi":"10.2147/IMCRJ.S543285","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Arnold-Chiari Malformation Type I (ACM-I) is a congenital disorder that can lead to severe neurological symptoms. While decompression surgery is the standard treatment, postoperative complications such as cerebrospinal fluid (CSF) leakage and infections can result in critical outcomes. Here, we report a case of septic shock following decompression surgery in a patient with ACM-I, emphasizing the challenges in postoperative critical care management.</p><p><strong>Case presentation: </strong>A 45-year-old woman with rheumatoid arthritis and progressive neurological symptoms underwent decompression surgery for ACM-I. On postoperative day five, CSF leakage was noted at the surgical site, accompanied by fever and leukocytosis. Despite broad-spectrum antibiotics, the patient developed septic shock, requiring mechanical ventilation and vasopressor support. CSF cultures revealed <i>Acinetobacter baumannii</i> infection, necessitating surgical debridement and intrathecal colistin. Despite aggressive management, the patient succumbed to septic shock.</p><p><strong>Conclusion: </strong>This case highlights the critical importance of early detection and aggressive management of postoperative infections in neurosurgical patients. The occurrence of CSF leakage and subsequent septic shock underscores the need for meticulous postoperative monitoring to prevent fatal complications. Timely intervention, including early microbiological assessment and individualized antibiotic therapy, is essential for improving outcomes in high-risk patients.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"1127-1134"},"PeriodicalIF":0.7000,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410383/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Medical Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/IMCRJ.S543285","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Arnold-Chiari Malformation Type I (ACM-I) is a congenital disorder that can lead to severe neurological symptoms. While decompression surgery is the standard treatment, postoperative complications such as cerebrospinal fluid (CSF) leakage and infections can result in critical outcomes. Here, we report a case of septic shock following decompression surgery in a patient with ACM-I, emphasizing the challenges in postoperative critical care management.

Case presentation: A 45-year-old woman with rheumatoid arthritis and progressive neurological symptoms underwent decompression surgery for ACM-I. On postoperative day five, CSF leakage was noted at the surgical site, accompanied by fever and leukocytosis. Despite broad-spectrum antibiotics, the patient developed septic shock, requiring mechanical ventilation and vasopressor support. CSF cultures revealed Acinetobacter baumannii infection, necessitating surgical debridement and intrathecal colistin. Despite aggressive management, the patient succumbed to septic shock.

Conclusion: This case highlights the critical importance of early detection and aggressive management of postoperative infections in neurosurgical patients. The occurrence of CSF leakage and subsequent septic shock underscores the need for meticulous postoperative monitoring to prevent fatal complications. Timely intervention, including early microbiological assessment and individualized antibiotic therapy, is essential for improving outcomes in high-risk patients.

Abstract Image

Abstract Image

Arnold-Chiari畸形I型术后感染性休克1例报告。
背景:Arnold-Chiari畸形I型(ACM-I)是一种先天性疾病,可导致严重的神经系统症状。虽然减压手术是标准的治疗方法,但术后并发症如脑脊液(CSF)泄漏和感染可导致严重后果。在这里,我们报告一例ACM-I患者减压手术后感染性休克,强调术后重症监护管理的挑战。病例介绍:一名45岁的女性,患有类风湿关节炎和进行性神经症状,接受了ACM-I减压手术。术后第5天,手术部位出现脑脊液漏,伴有发热和白细胞增多。尽管使用了广谱抗生素,患者还是出现了感染性休克,需要机械通气和血管加压药物支持。脑脊液培养显示鲍曼不动杆菌感染,需要手术清创和鞘内粘菌素。尽管进行了积极的治疗,病人还是死于感染性休克。结论:本病例强调了早期发现和积极处理神经外科患者术后感染的重要性。脑脊液渗漏和脓毒性休克的发生强调了术后严密监测以防止致命并发症的必要性。及时干预,包括早期微生物学评估和个体化抗生素治疗,对于改善高危患者的预后至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
International Medical Case Reports Journal
International Medical Case Reports Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
1.40
自引率
0.00%
发文量
135
审稿时长
16 weeks
期刊介绍: International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信