{"title":"The Transmission of Clostridioides (Clostridium) difficile with a One Health Perspective.","authors":"Su-Chen Lim, Thomas V Riley","doi":"10.1016/j.idc.2025.07.003","DOIUrl":null,"url":null,"abstract":"<p><p>Clostridioides difficile infection is a significant public health concern traditionally linked to health care settings. However, genomic evidence increasingly supports the spread of C difficile across humans, animals, food, and the environment with sources and reservoirs outside health care settings. Here, we review the transmission routes of C difficile within a One Health framework to uncover these complex interconnections. Understanding these pathways is essential for developing effective, integrated infection prevention and control strategies for health care and the community.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1000,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious disease clinics of North America","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.idc.2025.07.003","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Clostridioides difficile infection is a significant public health concern traditionally linked to health care settings. However, genomic evidence increasingly supports the spread of C difficile across humans, animals, food, and the environment with sources and reservoirs outside health care settings. Here, we review the transmission routes of C difficile within a One Health framework to uncover these complex interconnections. Understanding these pathways is essential for developing effective, integrated infection prevention and control strategies for health care and the community.
期刊介绍:
Infectious Disease Clinics of North America updates you on the latest trends in the clinical diagnosis and management of patients with infectious diseases, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Each issue focuses on a single topic in infectious disease, including clinical microbiology, compromised host infections, gastrointestinal infections, global health, hepatitis, HIV/AIDS, hospital-acquired infections, travel medicine, infection control, bacterial infections, sexually transmitted diseases, urinary tract infections, and viral infections.