Sara Mazzilli, Mathieu Tourdjman, Harold Noël, Anna Maisa, Isabelle Villena, Camille Le-Ray
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引用次数: 0
Abstract
Toxoplasmosis during pregnancy can cause congenital malformations and fetal death. This study aimed to estimate the Toxoplasma gondii seroprevalence among pregnant women participating in the 2021 French national perinatal survey and identify associated factors. All women giving birth in France during the study period were invited to participate. Data collected included demographic information, nationality, socio-economic status, education level, and Toxoplasma gondii serological status. Women were classified as seropositive if IgG antibodies were present or if seroconversion occurred during pregnancy. Univariate and multivariate Poisson regression analyses with robust error variance were used to estimate prevalence ratios and identify factors associated with seropositivity. Among 12,612 women, the overall seroprevalence was 25.9%, and 0.22% seroconverted during pregnancy. Seroprevalence increased by 5% with every 5-year age increment and was significantly higher in the French overseas territories of Mayotte (75.0%), La Réunion (35.8%), and French Guiana (33.3%). Seroprevalence was also higher among women with lower educational levels (47.4% for primary education) and those of Sub-Saharan African nationality (52.0%). Geographic and socio-demographic variations may reflect dietary and environmental diversity. Despite declining seroprevalence in France, continued public health efforts, particularly among high-risk populations, remain critical to minimize the impact of congenital toxoplasmosis.
期刊介绍:
Epidemiology & Infection publishes original reports and reviews on all aspects of infection in humans and animals. Particular emphasis is given to the epidemiology, prevention and control of infectious diseases. The scope covers the zoonoses, outbreaks, food hygiene, vaccine studies, statistics and the clinical, social and public-health aspects of infectious disease, as well as some tropical infections. It has become the key international periodical in which to find the latest reports on recently discovered infections and new technology. For those concerned with policy and planning for the control of infections, the papers on mathematical modelling of epidemics caused by historical, current and emergent infections are of particular value.