{"title":"The effect of sleep-oriented non-pharmacological interventions in preventing delirium: a systematic review of randomized controlled trials.","authors":"Ezgi Mutluay Yayla, Emine Kaplan Serin","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>To systematically review randomized controlled trials evaluating the efficacy of sleep-oriented non-pharmacological interventions for delirium prevention in intensive care units.</p><p><strong>Methods: </strong>We searched PubMed, Web of Science, Scopus, and the Cochrane Library for randomized controlled trials evaluating the efficacy of sleep-oriented, non-pharmacological interventions for delirium prevention in intensive care units published in English between 2019 and 2024. The methodological quality of the included studies was independently evaluated by two researchers using the Joanna Briggs Institute tool.</p><p><strong>Results: </strong>This review included eight randomized controlled trials (n = 649). Six studies assessed the effect of earplugs and masks on delirium prevention in intensive care patients. Three studies indicated that earplugs and eye masks effectively prevented delirium, while three studies found no effect. One study assessed the use of earplugs and masks as part of a bundle of interventions and reported a positive effect. Four studies showed an effect on sleep. None of the sleep-oriented non-pharmacological interventions assessed in these studies reported any harmful effects.</p><p><strong>Conclusion: </strong>Although several high-quality studies showed that these interventions significantly lowered delirium incidence, some trials found no effect, highlighting variability in outcomes.</p>","PeriodicalId":10796,"journal":{"name":"Croatian Medical Journal","volume":"66 4","pages":"289-298"},"PeriodicalIF":2.3000,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12426865/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Croatian Medical Journal","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: To systematically review randomized controlled trials evaluating the efficacy of sleep-oriented non-pharmacological interventions for delirium prevention in intensive care units.
Methods: We searched PubMed, Web of Science, Scopus, and the Cochrane Library for randomized controlled trials evaluating the efficacy of sleep-oriented, non-pharmacological interventions for delirium prevention in intensive care units published in English between 2019 and 2024. The methodological quality of the included studies was independently evaluated by two researchers using the Joanna Briggs Institute tool.
Results: This review included eight randomized controlled trials (n = 649). Six studies assessed the effect of earplugs and masks on delirium prevention in intensive care patients. Three studies indicated that earplugs and eye masks effectively prevented delirium, while three studies found no effect. One study assessed the use of earplugs and masks as part of a bundle of interventions and reported a positive effect. Four studies showed an effect on sleep. None of the sleep-oriented non-pharmacological interventions assessed in these studies reported any harmful effects.
Conclusion: Although several high-quality studies showed that these interventions significantly lowered delirium incidence, some trials found no effect, highlighting variability in outcomes.
目的:系统回顾评价以睡眠为导向的非药物干预在重症监护病房预防谵妄疗效的随机对照试验。方法:我们检索PubMed、Web of Science、Scopus和Cochrane图书馆,检索2019年至2024年间发表的英文对照试验,评估以睡眠为导向的非药物干预措施预防重症监护病房谵妄的疗效。纳入研究的方法学质量由两位研究人员使用乔安娜布里格斯研究所的工具独立评估。结果:本综述纳入8项随机对照试验(n = 649)。六项研究评估了耳塞和口罩对重症监护患者谵妄预防的影响。三项研究表明耳塞和眼罩能有效预防谵妄,而三项研究没有发现效果。一项研究评估了使用耳塞和口罩作为一系列干预措施的一部分,并报告了积极的效果。四项研究显示了对睡眠的影响。在这些研究中评估的以睡眠为导向的非药物干预措施均未报告有任何有害影响。结论:尽管一些高质量的研究表明这些干预措施显著降低了谵妄的发生率,但一些试验没有发现效果,突出了结果的可变性。
期刊介绍:
Croatian Medical Journal (CMJ) is an international peer reviewed journal open to scientists from all fields of biomedicine and health related research.
Although CMJ welcomes all contributions that increase and expand on medical knowledge, the two areas are of the special interest: topics globally relevant for biomedicine and health and medicine in developing and emerging countries.