Exploring the screening methods, prevalence, and risk factors of malnutrition in multiple sclerosis: A scoping review

IF 2.6 Q3 NUTRITION & DIETETICS

Clinical nutrition ESPEN Pub Date : 2025-09-05 DOI:10.1016/j.clnesp.2025.09.001

Tyler J. Titcomb , Farnoosh Shemirani , Tracey A. Cho , Linda G. Snetselaar

{"title":"Exploring the screening methods, prevalence, and risk factors of malnutrition in multiple sclerosis: A scoping review","authors":"Tyler J. Titcomb , Farnoosh Shemirani , Tracey A. Cho , Linda G. Snetselaar","doi":"10.1016/j.clnesp.2025.09.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Background & aims</h3><div>People with multiple sclerosis (MS) may be predisposed to malnutrition as several malnutrition risk factors are common among this group; however, evidence on malnutrition in MS is sparse. Therefore, the aim of the present study is to explore what is known about malnutrition in MS.</div></div><div><h3>Methods</h3><div>A scoping review was performed in 5 databases (Ovid Medline, Embase, Cochrane Central, Scopus, and the Web of Science Core Collection) in February 2024. Studies were included if they defined how malnutrition was evaluated or used a validated malnutrition screening tool among people with MS.</div></div><div><h3>Results</h3><div>Seven studies reported the prevalence at risk for malnutrition and eight reported the prevalence with malnutrition using several different methods to assess or screen for malnutrition including the Subjective Global Assessment (SGA), Patient-generated SGA, Mini Nutrition Assessment, Nutrition Risk Screening 2002, Global Leadership Initiative on Malnutrition criteria, serum albumin, and International Classification of Diseases taxonomy. One study reported prevalences based on two different methods; therefore, eight prevalences of risk for malnutrition and nine prevalences with malnutrition are reported. The reported prevalences at risk for malnutrition were 87.8 % and 85.5 %, 69.3 %, 57 %, 53.9 %, 24.8 %, 6.5 %, and 5.5 %. The reported prevalences of malnutrition were 15.5 % and 12.2 %, 13.4 %, 11.8 %, 10.4 %, 10.3 %, 1.6 %, 1.6 %, and 0.7 %. Several risk factors for malnutrition were reported including disability burden, age, and progressive subtype; however, bubble plots showed no associations for baseline age, sex distribution, MS duration, body mass index, or disability status. One study observed that malnutrition was associated with lower physical and mental quality of life.</div></div><div><h3>Conclusion</h3><div>The available evidence suggests that malnutrition may be common among people with MS; however, given the wide variation in reported prevalences more studies are needed to better evaluate the scope of malnutrition in MS.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"69 ","pages":"Pages 802-808"},"PeriodicalIF":2.6000,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical nutrition ESPEN","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405457725029225","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}

引用次数: 0

Abstract

Background & aims

People with multiple sclerosis (MS) may be predisposed to malnutrition as several malnutrition risk factors are common among this group; however, evidence on malnutrition in MS is sparse. Therefore, the aim of the present study is to explore what is known about malnutrition in MS.

Methods

A scoping review was performed in 5 databases (Ovid Medline, Embase, Cochrane Central, Scopus, and the Web of Science Core Collection) in February 2024. Studies were included if they defined how malnutrition was evaluated or used a validated malnutrition screening tool among people with MS.

Results

Seven studies reported the prevalence at risk for malnutrition and eight reported the prevalence with malnutrition using several different methods to assess or screen for malnutrition including the Subjective Global Assessment (SGA), Patient-generated SGA, Mini Nutrition Assessment, Nutrition Risk Screening 2002, Global Leadership Initiative on Malnutrition criteria, serum albumin, and International Classification of Diseases taxonomy. One study reported prevalences based on two different methods; therefore, eight prevalences of risk for malnutrition and nine prevalences with malnutrition are reported. The reported prevalences at risk for malnutrition were 87.8 % and 85.5 %, 69.3 %, 57 %, 53.9 %, 24.8 %, 6.5 %, and 5.5 %. The reported prevalences of malnutrition were 15.5 % and 12.2 %, 13.4 %, 11.8 %, 10.4 %, 10.3 %, 1.6 %, 1.6 %, and 0.7 %. Several risk factors for malnutrition were reported including disability burden, age, and progressive subtype; however, bubble plots showed no associations for baseline age, sex distribution, MS duration, body mass index, or disability status. One study observed that malnutrition was associated with lower physical and mental quality of life.

Conclusion

The available evidence suggests that malnutrition may be common among people with MS; however, given the wide variation in reported prevalences more studies are needed to better evaluate the scope of malnutrition in MS.

查看原文本刊更多论文

探讨多发性硬化症中营养不良的筛查方法、患病率和危险因素：一项范围综述。

背景与目的：多发性硬化症（MS）患者可能易患营养不良，因为几种营养不良危险因素在该人群中很常见；然而，关于多发性硬化症中营养不良的证据很少。因此，本研究的目的是探讨ms中营养不良的已知情况。方法：于2024年2月在5个数据库（Ovid Medline, Embase, Cochrane Central， Scopus和Web of Science Core Collection）中进行范围审查。如果研究定义了如何评估营养不良或在多发性硬化症患者中使用有效的营养不良筛查工具，则将其纳入研究。7项研究报告了营养不良风险的流行程度，8项研究报告了营养不良的流行程度，使用了几种不同的方法来评估或筛查营养不良，包括主观总体评估（SGA）、患者自行生成的SGA、迷你营养评估、2002年营养风险筛查、营养不良标准全球领导倡议、血清白蛋白和国际疾病分类。一项研究报告了基于两种不同方法的患病率；因此，报告了8个营养不良风险流行率和9个营养不良流行率。报告的营养不良危险患病率分别为87.8%和85.5%、69.3%、57%、53.9%、24.8%、6.5%和5.5%。报告的营养不良患病率分别为15.5%和12.2%、13.4%、11.8%、10.4%、10.3%、1.6%、1.6%和0.7%。报告了营养不良的几个危险因素，包括残疾负担、年龄和进行性亚型；然而，气泡图显示基线年龄、性别分布、MS持续时间、体重指数或残疾状况没有关联。一项研究发现，营养不良与较低的身体和精神生活质量有关。结论：现有证据表明，营养不良可能在多发性硬化症患者中普遍存在；然而，鉴于报告的患病率差异很大，需要更多的研究来更好地评估多发性硬化症中营养不良的范围。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical nutrition ESPEN NUTRITION & DIETETICS-

CiteScore

4.90

自引率

3.30%

发文量

512

期刊介绍： Clinical Nutrition ESPEN is an electronic-only journal and is an official publication of the European Society for Clinical Nutrition and Metabolism (ESPEN). Nutrition and nutritional care have gained wide clinical and scientific interest during the past decades. The increasing knowledge of metabolic disturbances and nutritional assessment in chronic and acute diseases has stimulated rapid advances in design, development and clinical application of nutritional support. The aims of ESPEN are to encourage the rapid diffusion of knowledge and its application in the field of clinical nutrition and metabolism. Published bimonthly, Clinical Nutrition ESPEN focuses on publishing articles on the relationship between nutrition and disease in the setting of basic science and clinical practice. Clinical Nutrition ESPEN is available to all members of ESPEN and to all subscribers of Clinical Nutrition.