Correlations between variability of preoperative ocular biometric measurements and accuracy of intraocular lens power calculation

IF 2.6 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-09-04 DOI:10.1016/j.pdpdt.2025.105210

Zhenqiang Lin , Ling Jin , Yue Wu , Wenxuan Wang , Ying Tang , Yijun Hu , Duanrong Cao

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引用次数: 0

Abstract

Objectives

To investigate the relationship between variability of preoperative ocular biometric measurements and the accuracy of intraocular lens (IOL) power calculation.

Methods

This retrospective study included cataract patients who underwent surgery at the People’s Hospital of Baoan Shenzhen from January 2022 to December 2024. Preoperative ocular biometric parameters were measured using the Lenstar LS-900, and the coefficients of variation (CV) of corneal curvature (K1-CV, K2-CV), axial length (AL-CV), anterior chamber depth (ACD-CV) were calculated. Intented residual refractive error (IRRE) was recorded. Postoperative spherical equivalent (SE), prediction error (PE = SE - IRRE), and absolute prediction error (APE = |PE|) were evaluated at one month postoperatively. The mean, median and interquartile range of PE and APE were calculated. Patients were divided into two groups based on the number of valid axial length measurements (Group 1: <3; Group 2: ≥3). Differences in age, sex, preoperative visual acuity (LogMAR VA), K1-CV, K2-CV, AL-CV, ACD-CV, PE, and APE were compared between the two groups. Spearman correlation was used to assess the relationship between biometric variability (K1-CV, K2-CV, AL-CV, ACD-CV) and refractive outcomes (PE and APE).

Results

A total of 118 eyes were included (Group 1: 44 eyes; Group 2: 74 eyes). Preoperative LogMAR VA was significantly worse in Group 1 than those in Group 2 (0.84 vs. 0.46, p < 0.001), but no significant differences were observed in age, sex, ACD, AL, mean keratometry (Km), PE, or APE between the two groups. Group 1 showed a mean PE of -0.13 and mean APE of 0.61, with 27.03 %, 39.19 %, and 50.0 % of eyes within ±0.25 D, ±0.50 D, and ±1.00 D of target refraction, respectively. In comparison, Group 2 demonstrated a lower mean PE (-1.80) and APE (0.48), and higher proportions of eyes within ±1.00 D (89.19 %). Variability in biometric parameters did not differ between the two groups (p ≥ 0.05). A weak correlation was found between preoperative VA and APE in Group 1 (r = 0.314, p = 0.038), but no significant correlations were detected between variability in biometric parameters with PE or APE.

Conclusions

The number of valid axial length measurements did not significantly affect preoperative ocular biometric variability or IOL power calculation accuracy in patients with cataract. Patients with fewer valid measurements (<3) had worse preoperative VA, which was weakly correlated with APE.

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术前眼部生物测量变化与人工晶状体度数计算准确性的相关性。

目的：探讨术前眼部生物特征测量的变异性与人工晶状体（IOL）度数计算准确性的关系。方法：对2022年1月至2024年12月在深圳市宝安人民医院行白内障手术的患者进行回顾性研究。术前使用Lenstar LS-900测量眼部生物特征参数，计算角膜曲率（K1-CV、K2-CV）、眼轴长度（AL-CV）、前房深度（ACD-CV）的变异系数（CV）。记录预期残余屈光不正（IRRE）。术后1个月评估术后球形当量（SE）、预测误差（PE = SE - IRRE）和绝对预测误差（APE = |PE|）。计算PE和APE的平均值、中位数和四分位数范围。根据有效眼轴长度测量数将患者分为两组(第一组：结果：共纳入118只眼（第一组：44只眼；第二组：74只眼）。组1术前LogMAR VA明显差于组2(0.84比0.46,p< 0.001)，但两组在年龄、性别、ACD、AL、平均角膜度数（Km）、PE、APE方面无显著差异。组1平均PE为-0.13，平均APE为0.61，目标屈光度在±0.25 D、±0.50 D和±1.00 D范围内的分别为27.03%、39.19%和50.0%。相比之下，第2组的平均PE（-1.80）和APE（0.48）较低，±1.00 D内的眼睛比例较高（89.19%）。两组间生物特征参数的变异性无差异（p≥0.05）。组1术前VA与APE呈弱相关（r = 0.314,p = 0.038），但生物特征参数变异性与PE或APE无显著相关。结论：有效的眼轴长度测量次数对白内障患者术前眼生物测量变异性或人工晶状体度数计算准确性没有显著影响。有效测量数据较少的患者(

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.