Effect of Monopolar Versus Bipolar Transurethral Resection of The Prostate on Erectile Function: A Randomized Controlled Trial with Phosphodiesterase-5 Inhibitors Users Subgroup Analysis.

IF 0.9 4区 医学 Q3 UROLOGY & NEPHROLOGY
Farbod Khorrami, Seyyed-Masoud Sadat, Mohammadreza Hajian, Farshad Gholipour
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引用次数: 0

Abstract

Purpose: Men with lower urinary tract symptoms (LUTS) from benign prostatic hyperplasia (BPH) often experience erectile dysfunction (ED). While transurethral resection of the prostate (TURP) can improve ED, new-onset ED remains a concern. This study compares monopolar (M-TURP) and bipolar (B-TURP) techniques, with a subgroup analysis based on phosphodiesterase-5 inhibitor (PDE5i) use.

Materials and methods: This randomized clinical trial included candidates for TURP who were over 50 years old. Patients were divided into M-TURP and B-TURP groups. Erectile function was assessed using the International Index of Erectile Function-15 (IIEF-15) at baseline, six weeks, and six months post-surgery.

Results: A total of 205 patients were analyzed (102 in the M-TURP group and 103 in the B-TURP group). Both groups showed no significant differences in baseline characteristics, perioperative findings, or surgical complications. IIEF-15 scores were comparable between groups at all time points. In the PDE5i user subgroup, M-TURP showed a slight short-term decline in erectile function and total scores at 6 weeks, but both groups demonstrated no significant long-term changes in ED at 6 months.

Conclusion: While no significant difference was observed in the impact of M-TURP and B-TURP on erectile function during medium-term follow-up, patients with a history of PDE5i usage may experience fewer adverse effects on their erectile function from B-TURP during the short-term follow-up.

单极与双极经尿道前列腺切除术对勃起功能的影响:磷酸二酯酶-5抑制剂使用者亚组分析的随机对照试验
目的:男性下尿路症状(LUTS)从良性前列腺增生(BPH)经常经历勃起功能障碍(ED)。虽然经尿道前列腺切除术(TURP)可以改善ED,但新发ED仍然值得关注。本研究比较了单极(M-TURP)和双极(B-TURP)技术,并进行了基于磷酸二酯酶-5抑制剂(PDE5i)使用的亚组分析。材料和方法:本随机临床试验纳入50岁以上的TURP候选人。患者分为M-TURP组和B-TURP组。在基线、术后6周和6个月,使用国际勃起功能指数-15 (IIEF-15)评估勃起功能。结果:共分析205例患者(M-TURP组102例,B-TURP组103例)。两组在基线特征、围手术期表现或手术并发症方面均无显著差异。IIEF-15分数在各组间各时间点具有可比性。在PDE5i使用者亚组中,M-TURP在6周时显示勃起功能和总分的短期轻微下降,但两组在6个月时均未显示ED的显着长期变化。结论:在中期随访中,M-TURP和B-TURP对勃起功能的影响无显著差异,但在短期随访中,有PDE5i使用史的患者B-TURP对勃起功能的不良影响较小。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Urology Journal
Urology Journal UROLOGY & NEPHROLOGY-
CiteScore
2.60
自引率
6.70%
发文量
44
审稿时长
6-12 weeks
期刊介绍: As the official journal of the Urology and Nephrology Research Center (UNRC) and the Iranian Urological Association (IUA), Urology Journal is a comprehensive digest of useful information on modern urology. Emphasis is on practical information that reflects the latest diagnostic and treatment techniques. Our objectives are to provide an exceptional source of current and clinically relevant research in the discipline of urology, to reflect the scientific work and progress of our colleagues, and to present the articles in a logical, timely, and concise format that meets the diverse needs of today’s urologist. Urology Journal publishes manuscripts on urology and kidney transplantation, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. Accordingly, original articles, case reports, and letters to editor are encouraged.
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