Bio-inspired synthesis and bio-activity of ruthenium nanoparticles from Tridax procumbens (Dagadi Pala) leaf extract

IF 4.1 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Nanoscale Research Letters Pub Date : 2025-09-07 DOI:10.1186/s11671-025-04300-z

Ajit Devale, Samadhan Nikalaje, Neeraj R. Prasad, Amit Varale

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引用次数: 0

Abstract

Herein, ruthenium nanoparticles (RuNPs) were synthesized using Tridax procumbens leaf extract as a reducing and stabilizing agent. The synthesis was optimized by adjusting temperature, leaf extract concentration, and reaction time. The synthesized RuNPs were characterized using UV-visible, XRD, EDAX, FTIR spectroscopy, SEM, and TEM, revealing uniform size and morphology. UV-visible spectroscopy confirmed RuNP formation with an absorption peak at 288 nm. FTIR analysis identified functional groups, with a peak at 600–800 cm^-1 indicating metallic Ru. XRD patterns showed peaks corresponding to RuNPs, with an average crystal size of 12.9 nm. SEM and TEM images revealed spherical RuNPs with an average diameter of 11.30 nm. The biological properties of the RuNPs were evaluated, demonstrating significant antibacterial and antifungal properties, and notable antioxidant activity. Antimicrobial activity was observed against Gram-positive bacteria (B. cereus, S. aureus) and Gram-negative bacteria (P. aeruginosa, E. coli) at concentrations of 50 µg/mL and above. The RuNPs showed antifungal activity against Candida albicans at 75 µg/ml and 100 µg/ml, but no activity against Aspergillus niger. The highest antioxidant activity was 77.13 ± 0.64% at a concentration of 100 µl. This study highlights the feasibility of utilizing Tridax procumbens leaf extract for the environmentally friendly synthesis of ruthenium nanoparticles, demonstrating their potential in biomedical applications and green chemistry.

Graphical abstract

Bio-inspired synthesis and bio-activity of ruthenium nanoparticles from Tridax procumbens leaf extract.

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原藜叶提取物中钌纳米颗粒的仿生合成及其生物活性研究

本文以原藜叶提取物为还原剂和稳定剂合成了纳米钌。通过调节温度、叶提取物浓度和反应时间对合成工艺进行优化。采用uv -可见、XRD、EDAX、FTIR、SEM、TEM等手段对合成的RuNPs进行了表征，发现其尺寸和形貌均匀。紫外可见光谱证实了RuNP的形成，吸收峰位于288 nm处。FTIR分析发现了官能团，在600-800 cm-1处有一个峰，表明是金属Ru。XRD谱图显示出与RuNPs相对应的峰，平均晶粒尺寸为12.9 nm。扫描电镜和透射电镜显示平均直径为11.30 nm的球形RuNPs。对RuNPs的生物学特性进行了评价，显示出显著的抗菌和抗真菌特性，以及显著的抗氧化活性。在50µg/mL及以上浓度下，对革兰氏阳性菌（蜡样芽孢杆菌、金黄色葡萄球菌）和革兰氏阴性菌（铜绿假单胞菌、大肠杆菌）均有抑菌活性。在75µg/ml和100µg/ml浓度下，RuNPs对白色念珠菌有抗真菌活性，但对黑曲霉没有活性。当浓度为100µl时，其抗氧化活性最高，为77.13±0.64%。本研究强调了利用原藜叶提取物环保合成纳米钌的可行性，展示了其在生物医学和绿色化学方面的应用潜力。原藜叶提取物中钌纳米颗粒的仿生合成及其生物活性研究。

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来源期刊

Nanoscale Research Letters 工程技术-材料科学：综合

CiteScore

11.30

自引率

0.00%

发文量

110

审稿时长

48 days

期刊介绍： Nanoscale Research Letters (NRL) provides an interdisciplinary forum for communication of scientific and technological advances in the creation and use of objects at the nanometer scale. NRL is the first nanotechnology journal from a major publisher to be published with Open Access.