VO₂ Max in Clinical Cardiology: Clinical Applications, Evidence Gaps, and Future Directions.

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Cardiology Reports Pub Date : 2025-09-06 DOI:10.1007/s11886-025-02289-6

Hesham M Abdalla, Luke Dreher, Hunter VanDolah, Adam Bacon, Mohammed El-Nayir, Mahmoud Abdelnabi, Ramzi Ibrahim, Hoang Nhat Pham, George Bcharah, Girish Pathangey, Courtney Wheatley-Guy, Satyajit Reddy, Juan Farina, Chadi Ayoub, Reza Arsanjani

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引用次数: 0

Abstract

Purpose of review: VO₂ max is a fundamental marker of cardiorespiratory fitness with substantial prognostic and diagnostic value within the field of cardiology. This review analyzes current and emerging evidence regarding its clinical uses, highlights key evidence gaps, and explores emerging developments poised to broaden its clinical application.

Recent findings: Evidence supports VO2 max as a powerful independent predictor for heart failure, coronary artery disease, hypertrophic cardiomyopathy, and cardiac amyloidosis, supporting it use in identifying high-risk patients for advanced interventions. Recent developments including the integration of machine learning and wearable devices can facilitate accurate VO2 estimation in routine clinical practice without the necessity of specialized diagnostic tools. Despite its robust diagnostic and prognostic value, VO₂ max assessment remains underutilized in routine cardiovascular care, primarily due to the need for specialized equipment and personnel. Future research should explore emerging technological innovations for VO2 max estimation and the development of evidence-based protocols to support its broader clinical implementation for improved cardiovascular outcomes.

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VO2 Max在临床心脏病学中的应用：临床应用、证据差距和未来方向。

综述目的：vo2max是心血管健康的基本指标，在心脏病学领域具有重要的预后和诊断价值。本综述分析了目前和新出现的关于其临床应用的证据，突出了关键的证据差距，并探讨了有望扩大其临床应用的新兴发展。最新发现：有证据支持最大摄氧量是心力衰竭、冠状动脉疾病、肥厚性心肌病和心脏淀粉样变性的一个强大的独立预测指标，支持将其用于识别高风险患者并进行高级干预。最近的发展包括机器学习和可穿戴设备的集成，可以在常规临床实践中促进准确的VO2估计，而无需专门的诊断工具。尽管具有强大的诊断和预后价值，但由于需要专门的设备和人员，vo2max评估在常规心血管护理中仍未得到充分利用。未来的研究应该探索VO2 max估计的新兴技术创新和基于证据的方案的发展，以支持其更广泛的临床实施，以改善心血管结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Cardiology Reports CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

6.20

自引率

2.70%

发文量

209

期刊介绍： The aim of this journal is to provide timely perspectives from experts on current advances in cardiovascular medicine. We also seek to provide reviews that highlight the most important recently published papers selected from the wealth of available cardiovascular literature. We accomplish this aim by appointing key authorities in major subject areas across the discipline. Section editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.