Hyeok-Jun Gwon , Wonho Lee , Sang-Hyoun Choi , Kum Bae Kim
{"title":"Feasibility and limitations of a postal dosimetry audit system using RPLGD for high-dose-rate brachytherapy","authors":"Hyeok-Jun Gwon , Wonho Lee , Sang-Hyoun Choi , Kum Bae Kim","doi":"10.1016/j.radphyschem.2025.113285","DOIUrl":null,"url":null,"abstract":"<div><div>International recommendations and South Korean regulations emphasize the need for dosimetry audit systems to ensure treatment accuracy in high-dose-rate brachytherapy. In this study, we designed and tested a prototype polycarbonate postal audit phantom to assess its feasibility. Using six GD-302M radiophotoluminescent glass dosimeters. Dose measurements were performed at points A and B based on the treatment planning system (TPS) and PHITS. These were validated in the Korea laboratory accreditation scheme and secondary standard dosimetry laboratory using Co-60 beam. Reproducibility and linearity tests showed stable responses; however, a maximum deviation of 13.5 % was observed between the measured and TPS doses at point A. The PHITS simulations revealed that the TPS overestimated the dose by approximately 10 %, whereas glass dosimeters showed up to 20 % overestimation because of low-energy gamma rays from the Ir-192 source. Additional water phantom measurements demonstrated that the RPLGD can provide reasonably consistent dose readings under water-equivalent conditions. The discrepancies observed in the audit phantom were found to follow a consistent trend and could be assessed using normalization. The combined expanded uncertainties were calculated as 3.1 % and 3.2 % (<em>k</em> = <em>2</em>) for the source holder models 70010 and 72280, respectively. The audit phantom showed potential for application in nationwide postal audits, pending further validation. To ensure clinical applicability, future work should focus on addressing the energy dependence of the RPLGD and conducting a multi-institutional pilot study.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"239 ","pages":"Article 113285"},"PeriodicalIF":2.8000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiation Physics and Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0969806X25007777","RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
International recommendations and South Korean regulations emphasize the need for dosimetry audit systems to ensure treatment accuracy in high-dose-rate brachytherapy. In this study, we designed and tested a prototype polycarbonate postal audit phantom to assess its feasibility. Using six GD-302M radiophotoluminescent glass dosimeters. Dose measurements were performed at points A and B based on the treatment planning system (TPS) and PHITS. These were validated in the Korea laboratory accreditation scheme and secondary standard dosimetry laboratory using Co-60 beam. Reproducibility and linearity tests showed stable responses; however, a maximum deviation of 13.5 % was observed between the measured and TPS doses at point A. The PHITS simulations revealed that the TPS overestimated the dose by approximately 10 %, whereas glass dosimeters showed up to 20 % overestimation because of low-energy gamma rays from the Ir-192 source. Additional water phantom measurements demonstrated that the RPLGD can provide reasonably consistent dose readings under water-equivalent conditions. The discrepancies observed in the audit phantom were found to follow a consistent trend and could be assessed using normalization. The combined expanded uncertainties were calculated as 3.1 % and 3.2 % (k = 2) for the source holder models 70010 and 72280, respectively. The audit phantom showed potential for application in nationwide postal audits, pending further validation. To ensure clinical applicability, future work should focus on addressing the energy dependence of the RPLGD and conducting a multi-institutional pilot study.
期刊介绍:
Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing.
The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.