Plasmonic resonance-enhanced photoelectrochemical dopamine sensing using ZIF-8 supported Ag nanoparticles

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchemical Journal Pub Date : 2025-09-02 DOI:10.1016/j.microc.2025.115064

Dawei Yan , Xiaoxia Zhou , Xiaoqing Jia , Shige Wang

{"title":"Plasmonic resonance-enhanced photoelectrochemical dopamine sensing using ZIF-8 supported Ag nanoparticles","authors":"Dawei Yan , Xiaoxia Zhou , Xiaoqing Jia , Shige Wang","doi":"10.1016/j.microc.2025.115064","DOIUrl":null,"url":null,"abstract":"<div><div>Dopamine (DA), as a key neurotransmitter, is correlated with neurological disorders, including Parkinson's disease and schizophrenia. In this work, we presented an Ag/ZIF-8-based photoelectrochemical (PEC) biosensor that significantly enhanced DA detection performance. The synergistic effect between Ag nanoparticles (NPs) and ZIF-8 not only facilitates rapid electron transport but also leverages the localized surface plasmon resonance (LSPR) effect of Ag NPs. Under light illumination, this unique PEC sensor boosts DA detection sensitivity by 3.54-fold compared to conventional electrochemical methods. Furthermore, the biosensor demonstrates super performance, including an ultra-wide linear range (0.1–400 μM), high selectivity (0.31748 μA μM<sup>−1</sup>), a low detection limit (18 nM, S/N = 3), outstanding anti-interference capability, and remarkable stability (>98 % signal retention after 30 days). This work a new strategy for the development of efficient and stable biomolecular photoelectrochemical sensing platforms, and has significant application potential in the fields of neurotransmitter monitoring and disease diagnosis.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115064"},"PeriodicalIF":4.9000,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchemical Journal","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0026265X25024129","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Dopamine (DA), as a key neurotransmitter, is correlated with neurological disorders, including Parkinson's disease and schizophrenia. In this work, we presented an Ag/ZIF-8-based photoelectrochemical (PEC) biosensor that significantly enhanced DA detection performance. The synergistic effect between Ag nanoparticles (NPs) and ZIF-8 not only facilitates rapid electron transport but also leverages the localized surface plasmon resonance (LSPR) effect of Ag NPs. Under light illumination, this unique PEC sensor boosts DA detection sensitivity by 3.54-fold compared to conventional electrochemical methods. Furthermore, the biosensor demonstrates super performance, including an ultra-wide linear range (0.1–400 μM), high selectivity (0.31748 μA μM⁻¹), a low detection limit (18 nM, S/N = 3), outstanding anti-interference capability, and remarkable stability (>98 % signal retention after 30 days). This work a new strategy for the development of efficient and stable biomolecular photoelectrochemical sensing platforms, and has significant application potential in the fields of neurotransmitter monitoring and disease diagnosis.

Abstract Image

查看原文本刊更多论文

利用ZIF-8负载的银纳米颗粒等离子共振增强光电化学多巴胺传感

多巴胺（DA）作为一种关键的神经递质，与神经系统疾病有关，包括帕金森病和精神分裂症。在这项工作中，我们提出了一种基于Ag/ zif -8的光电化学（PEC）生物传感器，该传感器显著提高了DA检测性能。Ag纳米粒子（NPs）与ZIF-8之间的协同效应不仅促进了电子的快速传递，而且利用了Ag纳米粒子的局部表面等离子体共振（LSPR）效应。在光照下，与传统电化学方法相比，这种独特的PEC传感器将DA检测灵敏度提高了3.54倍。此外，该生物传感器具有超宽线性范围（0.1 ~ 400 μM）、高选择性（0.31748 μA μM−1）、低检出限（18 nM, S/N = 3）、出色的抗干扰能力和卓越的稳定性（30天后信号保持率>； 98%）。本研究为开发高效、稳定的生物分子光电电化学传感平台提供了新思路，在神经递质监测和疾病诊断等领域具有重要的应用潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Microchemical Journal 化学-分析化学

CiteScore

8.70

自引率

8.30%

发文量

1131

审稿时长

1.9 months

期刊介绍： The Microchemical Journal is a peer reviewed journal devoted to all aspects and phases of analytical chemistry and chemical analysis. The Microchemical Journal publishes articles which are at the forefront of modern analytical chemistry and cover innovations in the techniques to the finest possible limits. This includes fundamental aspects, instrumentation, new developments, innovative and novel methods and applications including environmental and clinical field. Traditional classical analytical methods such as spectrophotometry and titrimetry as well as established instrumentation methods such as flame and graphite furnace atomic absorption spectrometry, gas chromatography, and modified glassy or carbon electrode electrochemical methods will be considered, provided they show significant improvements and novelty compared to the established methods.