Moisture-associated skin damage and its management in neonatal and infant populations: a retrospective study in Italy.

IF 1.7 4区医学 Q3 DERMATOLOGY

Journal of wound care Pub Date : 2025-09-02 DOI:10.12968/jowc.2025.0178

Biagio Nicolosi, Eustachio Parente, Alessio Petronici, Leonardo Fioravanti, Simona Cavalieri, Vincenzo Nobile, Giorgio Reggiardo, Riccardo Coletta, Marco Moroni, Guido Ciprandi

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引用次数: 0

Abstract

Objective: Moisture-associated skin damage (MASD) is a significant concern in the paediatric population, particularly among neonates, who exhibit the highest incidence due to their highly sensitive and fragile skin. The aim of the study was to identify the most effective treatment.

Method: A retrospective observational study was conducted at Meyer Children's Hospital IRCCS, Florence, Italy. Data from infants admitted to the neonatal intensive care unit of the hospital were collected from electronic health records. Demographic, clinical and nursing data were analysed to identify the key clinical features of MASD lesions, including their severity, healing time, and the relationship between MASD lesions and treatment approaches.

Results: The cohort comprised 102 infants (mean age 2.92 months). Incontinence-associated dermatitis (IAD) accounted for the majority (78.4%) of MASD lesions. Among patients with IAD, most exhibited persistent redness (26.3%) or skin loss (47.5%) without clinical signs of infection. In contrast, peristomal MASD cases constituted 21.6% of the total, with the majority classified according to the Study on Peristomal Skin Alterations (SACS) 2.0 as L2 erosive lesions (63.6%), predominantly occurring in quadrants 2, 3 or 5. A novel treatment (Vulnamin; Professional Dietetics S.p.A., Italy) was used to manage MASD lesions in 64.7% of patients. This innovative treatment significantly (p<0.001) reduced healing time by an average of 2.4 days and decreased the odds of relapse by 5.3 times compared with traditional treatments.

Conclusion: The findings of this study showed that use of effective MASD therapies can reduce healing time and relapse rate, leading to decreased nursing hours and associated costs.

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新生儿和婴儿人群中与水分相关的皮肤损伤及其管理：意大利的一项回顾性研究。

目的：水分相关性皮肤损伤（MASD）是儿科人群的一个重要问题，特别是在新生儿中，由于其高度敏感和脆弱的皮肤，新生儿的发病率最高。这项研究的目的是确定最有效的治疗方法。方法：在意大利佛罗伦萨Meyer儿童医院IRCCS进行回顾性观察研究。入院新生儿重症监护病房的婴儿数据从电子健康记录中收集。对人口统计学、临床和护理数据进行分析，以确定MASD病变的关键临床特征，包括其严重程度、愈合时间以及MASD病变与治疗方法之间的关系。结果：该队列包括102名婴儿（平均年龄2.92个月）。尿失禁相关性皮炎（IAD）占MASD病变的大多数（78.4%）。在IAD患者中，大多数表现为持续发红（26.3%）或皮肤脱落（47.5%），没有感染的临床体征。相比之下，胃周围MASD病例占21.6%，大多数根据研究胃周围皮肤改变（SACS） 2.0分类为L2糜烂性病变（63.6%），主要发生在象限2、3或5。64.7%的患者使用了一种新的治疗方法（Vulnamin; Professional Dietetics S.p.A, Italy）来治疗MASD病变。结论：本研究结果表明，使用有效的MASD疗法可以缩短愈合时间和复发率，从而减少护理时间和相关费用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of wound care DERMATOLOGY-

CiteScore

2.90

自引率

10.50%

发文量

215

期刊介绍： Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice. In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers. Specifically, JWC publishes: High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments Clinical case studies providing information on how to deal with complex wounds Comprehensive literature reviews on current concepts and practice, including cost-effectiveness Updates on the activities of wound care societies around the world.