Prevalence and incidence of systemic lupus erythematosus in Thailand based on national health data.

IF 3.5 2区 医学 Q1 RHEUMATOLOGY
Patnarin Pongkulkiat, Chingching Foocharoen, Tippawan Onchan, Siraphop Suwannaroj, Ajanee Mahakkanukrauh
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引用次数: 0

Abstract

Background: SLE is an autoimmune disease that varies across ethnic populations and the regions that cause economic burdens, but nationwide epidemiological data for Thailand are lacking.

Objective: To estimate the incidence and prevalence of SLE in Thailand between 2017 and 2020.

Methods: A retrospective cohort study used the Information and Communication Technology Center, Ministry of Public Health, covering all major healthcare insurance systems (nearly 90% of hospitals, about 80% of the Thai population). Adults (≥18 years) with a primary diagnosis of SLE (International Classification of Diseases 10th Revision code M32) were included. Point and period prevalence (per 100 000 population) and annual incidence rates (per 100 000 person-years) were calculated overall and stratified by year, age, sex and region, with 95% CIs.

Results: In 2017, 55 956 prevalent cases were identified among 65 204 797 of the total Thai population, yielding a point prevalence of 85.8/100 000 (95 % CI 85.1 to 86.5). Prevalence was highest in women (152.9 vs 15.9/100 000; female-to-male ratio 9.6:1), in the 40-49 year age group (128.3/100 000) and in the southern region (178.5/100 000). From 2018 to 2020, incident SLE cases numbered 15 403, 16 243 and 15 925, corresponding to annual incidence rates of 23.6, 24.8 and 24.3/100 000 person-years, and the cumulative incidence for the 3 years was 72.7/100 000 person-years (95 % CI 72.0 to 73.4). Incidence peaked at ages 40-49 in 2019 (33.7/100 000) and was consistently highest in the south (60.0, 53.9 and 57.3/100 000 person-years in 2018-2020).

Conclusions: SLE is relatively common in Thailand, particularly among women of reproductive age and residents of the southern region. These nationwide data support SLE service planning in Thailand and may guide resource allocation in other Southeast Asian health systems expanding universal coverage.

Abstract Image

基于国家卫生数据的泰国系统性红斑狼疮患病率和发病率。
背景:SLE是一种自身免疫性疾病,在不同民族人群和造成经济负担的地区有所不同,但缺乏泰国全国范围的流行病学数据。目的:估计2017年至2020年泰国SLE的发病率和患病率。方法:采用公共卫生部信息与通信技术中心的回顾性队列研究,涵盖所有主要医疗保险系统(近90%的医院,约80%的泰国人口)。初步诊断为SLE(国际疾病分类第十版修订代码M32)的成人(≥18岁)被纳入研究。点和时期患病率(每10万人)和年发病率(每10万人年)被整体计算并按年、年龄、性别和地区分层,95% ci。结果:2017年,在泰国总人口的65 204 797人中发现了55 956例流行病例,点患病率为85.8/10万(95% CI为85.1至86.5)。女性患病率最高(152.9 vs 15.9/10万;男女比例为9.6:1),40-49岁年龄组患病率最高(128.3/10万),南部地区患病率最高(178.5/10万)。2018 - 2020年,SLE发病例数分别为15 403、16 243和15 925例,年均发病率分别为23.6、24.8和24.3/10万人-年,3年累计发病率为72.7/10万人-年(95% CI 72.0 ~ 73.4)。2019年,40-49岁的发病率达到高峰(33.7/10万人),南方的发病率一直最高(2018-2020年分别为60.0、53.9和57.3/10万人年)。结论:SLE在泰国较为常见,尤其是育龄妇女和南部地区居民。这些全国性的数据支持泰国的SLE服务规划,并可能指导其他东南亚卫生系统扩大全民覆盖的资源分配。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Lupus Science & Medicine
Lupus Science & Medicine RHEUMATOLOGY-
CiteScore
5.30
自引率
7.70%
发文量
88
审稿时长
15 weeks
期刊介绍: Lupus Science & Medicine is a global, peer reviewed, open access online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all aspects of lupus and related diseases. It is the first lupus-specific open access journal in the world and was developed in response to the need for a barrier-free forum for publication of groundbreaking studies in lupus. The journal publishes research on lupus from fields including, but not limited to: rheumatology, dermatology, nephrology, immunology, pediatrics, cardiology, hepatology, pulmonology, obstetrics and gynecology, and psychiatry.
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