Multi-Modal Lung Cancer Detection Using Pyramidal Cascade Neuro-Fuzzy Fractional Network.

IF 1.9 4区 医学 Q3 ONCOLOGY
Cancer Investigation Pub Date : 2025-08-01 Epub Date: 2025-09-05 DOI:10.1080/07357907.2025.2520610
Ramachandran A, Michael Mahesh K, Vijayan Panneerselvam, S V J Mani
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引用次数: 0

Abstract

Lung cancer detection (LCD) is a process of identifying an occurrence of lung cancer (LC) or irregularities in the lungs. Early detection of lung cancer is crucial for improving patient survival and enabling effective treatment. Computed Tomography (CT) images and Positron emission tomography (PET) are employed for screening and detecting LC. These methods offer full cross-sectional images of the lungs to detect smaller lesions. Several techniques are developed for LCD, but they often fall into uncertainty. Therefore, a Pyramidal Cascade Neuro-Fuzzy Fractional Network (PCNFFN) is introduced for LCD utilizing CT and PET images. Initially, PET and CT images are pre-processed employing a Bilateral filter (BF). Then, lung lobes are segmented from both images utilizing Dual-Attention V-Network (DAV-Net). Thereafter, Black Hole Entropic Fuzzy Clustering (BHEFC) is employed to segment tumor locations from both lung lobe segmented images. Next, features are extracted from tumor location segmented images. Lastly, LCD is performed by PCNFFN. However, PCNFFN is a combination of Deep Pyramidal residual Network (PyramidNet) and Cascade Neuro-Fuzzy Network (NFN) with Fractional Calculus (FC). In addition, PCNFFN achieved an accuracy of about 91.002%, a true negative rate (TNR) of about 90.504% and a true positive rate (TPR) of about 92.571%.

基于金字塔级联神经模糊分数网络的多模态肺癌检测。
肺癌检测(LCD)是一种识别肺癌(LC)发生或肺部不规则的过程。肺癌的早期发现对于提高患者生存率和有效治疗至关重要。计算机断层扫描(CT)图像和正电子发射断层扫描(PET)用于筛选和检测LC。这些方法提供肺部的全横断面图像,以发现较小的病变。目前已经开发了几种LCD技术,但往往存在不确定性。为此,提出了一种基于CT和PET图像的金字塔级联神经模糊分数网络(PCNFFN)。首先,PET和CT图像采用双边滤波器(BF)进行预处理。然后,利用双注意力v网络(Dual-Attention V-Network, DAV-Net)对两幅图像进行肺叶分割。然后,利用黑洞熵模糊聚类(Black Hole Entropic Fuzzy Clustering, BHEFC)对两幅肺叶分割图像进行肿瘤位置分割。其次,从肿瘤定位分割图像中提取特征。最后,采用PCNFFN实现LCD显示。然而,PCNFFN是深度金字塔残差网络(PyramidNet)和具有分数阶微积分(FC)的级联神经模糊网络(NFN)的结合。此外,PCNFFN的准确率约为91.002%,真阴性率(TNR)约为90.504%,真阳性率(TPR)约为92.571%。
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来源期刊
Cancer Investigation
Cancer Investigation 医学-肿瘤学
CiteScore
3.80
自引率
4.20%
发文量
71
审稿时长
8.5 months
期刊介绍: Cancer Investigation is one of the most highly regarded and recognized journals in the field of basic and clinical oncology. It is designed to give physicians a comprehensive resource on the current state of progress in the cancer field as well as a broad background of reliable information necessary for effective decision making. In addition to presenting original papers of fundamental significance, it also publishes reviews, essays, specialized presentations of controversies, considerations of new technologies and their applications to specific laboratory problems, discussions of public issues, miniseries on major topics, new and experimental drugs and therapies, and an innovative letters to the editor section. One of the unique features of the journal is its departmentalized editorial sections reporting on more than 30 subject categories covering the broad spectrum of specialized areas that together comprise the field of oncology. Edited by leading physicians and research scientists, these sections make Cancer Investigation the prime resource for clinicians seeking to make sense of the sometimes-overwhelming amount of information available throughout the field. In addition to its peer-reviewed clinical research, the journal also features translational studies that bridge the gap between the laboratory and the clinic.
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