Abidan Abulimiti , Bryce N. Balmain , Jessica N. Alcala , Raksa B. Moran , Chetan Dholakiya , Raquel Cavazos , Lindsey Elwell , Marcus Payne , Rebekah Summerall Woodward , Satyam Sarma , Valentin Mons , Andrew R. Tomlinson , Tony G. Babb
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引用次数: 0
Abstract
We examined the exercise ventilatory response to heavy exercise (ventilation [V̇E] and carbon dioxide elimination [V̇CO2] relationship from ventilatory threshold to peak exercise) and operational lung volumes (end expiratory [EELV] and end inspiratory [EILV]) in older adults with and without obesity. Forty-nine older adults with (BMI: 33.9 ± 5.0 kg/m2, age: 70 ± 2 y) and without obesity (BMI: 24.6 ± 3.0 kg/m2, age:71 ± 3 y) were evaluated, and performed a maximal incremental cycling test. The V̇E/V̇CO2 slope was lower in those with (43.1 ± 8.0) vs. without obesity (51.4 ± 11.1). While EELV was lower in those with (52.4 ± 6.1 %TLC) vs. without obesity (58.9 ± 5.8 %TLC), EILV was similar (with obesity: 88.2 ± 4.5 vs. without obesity: 89.2 ± 4.2 %TLC) between groups. EELV increased more from rest to peak exercise in those with obesity (0.23 ± 0.30 L: vs. −0.1 ± 0.4 L). Our findings demonstrate that the ventilatory response to heavy exercise is blunted in older adults with obesity, which appears to be associated with an increasing EILV encroaching on TLC.
期刊介绍:
Respiratory Physiology & Neurobiology (RESPNB) publishes original articles and invited reviews concerning physiology and pathophysiology of respiration in its broadest sense.
Although a special focus is on topics in neurobiology, high quality papers in respiratory molecular and cellular biology are also welcome, as are high-quality papers in traditional areas, such as:
-Mechanics of breathing-
Gas exchange and acid-base balance-
Respiration at rest and exercise-
Respiration in unusual conditions, like high or low pressure or changes of temperature, low ambient oxygen-
Embryonic and adult respiration-
Comparative respiratory physiology.
Papers on clinical aspects, original methods, as well as theoretical papers are also considered as long as they foster the understanding of respiratory physiology and pathophysiology.