Improving broad-spectrum resistance to clubroot disease with one gene

IF 29 1区生物学 Q1 GENETICS & HEREDITY

Nature genetics Pub Date : 2025-09-05 DOI:10.1038/s41588-025-02304-0

引用次数: 0

Abstract

GSL5, a glucan synthase, acts as a suppressor of jasmonic acid-mediated immunity in cruciferous plants. Inactivation of GSL5 by genome editing confers high-level and broad-spectrum resistance to pathogens that cause clubroot disease in four cruciferous species.

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用一个基因提高对根茎病的广谱抗性

GSL5是一种葡聚糖合成酶，可抑制十字花科植物茉莉酸介导的免疫。通过基因组编辑使GSL5失活，可在四种十字花科植物中获得对导致棍棒病的病原体的高水平和广谱抗性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature genetics 生物-遗传学

CiteScore

43.00

自引率

2.60%

发文量

241

审稿时长

3 months

期刊介绍： Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation. Integrative genetic topics comprise, but are not limited to: -Genes in the pathology of human disease -Molecular analysis of simple and complex genetic traits -Cancer genetics -Agricultural genomics -Developmental genetics -Regulatory variation in gene expression -Strategies and technologies for extracting function from genomic data -Pharmacological genomics -Genome evolution