{"title":"Cardiopulmonary Exercise Testing in Dysfunctional Breathing: A Case Series of Five Young Women.","authors":"Arup Haldar, Raja Dhar, Diptendu Dey, Amrita Bhattacharya, Beauty Biswas, Shyam Krishnan","doi":"10.1002/rcr2.70336","DOIUrl":null,"url":null,"abstract":"<p><p>Dysfunctional breathing (DB) is an underdiagnosed condition in young patients presenting with unexplained exertional breathlessness. Cardiopulmonary exercise testing (CPET) provides valuable diagnostic insights in these challenging cases. We present a case series of five young women (mean age 23.2 years) who underwent comprehensive evaluation including CPET and body plethysmography for persistent exertional dyspnea. All patients demonstrated characteristic CPET findings of oscillatory breathing patterns, preserved ventilatory reserve, elevated VE/VCO<sub>2</sub> slope, and absence of oxygen desaturation. Body plethysmography revealed consistently elevated residual volumes (162%-296% predicted) and RV/TLC ratios (40.39%-50.21%). CPET is crucial for diagnosing DB in young patients with unexplained dyspnea. The consistent plethysmography abnormalities suggest potential underlying airway pathology or maladaptive breathing patterns.</p>","PeriodicalId":45846,"journal":{"name":"Respirology Case Reports","volume":"13 9","pages":"e70336"},"PeriodicalIF":0.8000,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399361/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respirology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/rcr2.70336","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
引用次数: 0
Abstract
Dysfunctional breathing (DB) is an underdiagnosed condition in young patients presenting with unexplained exertional breathlessness. Cardiopulmonary exercise testing (CPET) provides valuable diagnostic insights in these challenging cases. We present a case series of five young women (mean age 23.2 years) who underwent comprehensive evaluation including CPET and body plethysmography for persistent exertional dyspnea. All patients demonstrated characteristic CPET findings of oscillatory breathing patterns, preserved ventilatory reserve, elevated VE/VCO2 slope, and absence of oxygen desaturation. Body plethysmography revealed consistently elevated residual volumes (162%-296% predicted) and RV/TLC ratios (40.39%-50.21%). CPET is crucial for diagnosing DB in young patients with unexplained dyspnea. The consistent plethysmography abnormalities suggest potential underlying airway pathology or maladaptive breathing patterns.
期刊介绍：
Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
