Clinical efficacy and mechanism of Bletilla striata and Chinese herbal compounds in treatment of peptic ulcer.

Abstract

Peptic ulcer (PU) is characterized by inflammation, necrosis, and erosion of the gastrointestinal mucosa caused by various pathogenic factors, leading to ulcer formation. The stomach and duodenum are the most commonly affected sites. Bletilla striata, a traditional Chinese medicinal herb, contains diverse chemical constituents and exhibits multiple pharmacological effects. As a key component in various traditional Chinese medicine compound formulations, it has demonstrated notable clinical efficacy. Moreover, it has a solid research foundation and broad application prospects in the treatment of gastrointestinal diseases. This paper systematically elaborates on the clinical efficacy and mechanisms of action of Bletilla striata in the treatment of PUs, drawing from ancient medical literature and traditional formula applications to provide support for clinical use.